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Gene Expression Data
Assay Details
Assay
Reference: J:294646 Stupnikov MR, et al., Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation. Elife. 2019 Oct 21;8:e50487
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6695148
Gene symbol: Fut4
Gene name: fucosyltransferase 4
Antibody: Anti-Stage-Specific Embryonic Antigen-1 Antibody, clone MC-480
Detection system: Secondary antibody
Results
Specimen 3B control: embryonic day 18.5 (more )
Note: Triple labeled: red - Fut4; Cyan - Calca (assay MGI:6695177); green - Scgb3a2 (assay MGI:6695149).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present 3B control Expressed in secretory precursors.
Specimen 3B Jag1 cnull: embryonic day 18.5; Jag1tm1Jlew/Jag1tm1Jlew, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Triple labeled: red - Fut4; Cyan - Calca (assay MGI:6695177); green - Scgb3a2 (assay MGI:6695149).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present 3B Jag1cKO Expressed in secretory precursors, similar as in the control.
Specimen 3B Jag2 cnull: embryonic day 18.5; Jag2tm2.1Grid/Jag2tm2.1Grid, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Triple labeled: red - Fut4; Cyan - Calca (assay MGI:6695177); green - Scgb3a2 (assay MGI:6695149).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present 3B Jag2cKO Expressed in secretory precursors, similar as in the control.
Specimen 3B Jag1/2 cnull: embryonic day 18.5; Jag1tm1Jlew/Jag1tm1Jlew, Jag2tm2.1Grid/Jag2tm2.1Grid, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Triple labeled: red - Fut4; Cyan - Calca (assay MGI:6695177); green - Scgb3a2 (assay MGI:6695149).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present Clusters 3B Jag1/2cKO Expressed only in secretory precursors tightly associated with the developing neuroepithelial bodies. Nearly absent expression outside the neuroepithelial bodies.
Specimen 3C control: embryonic day 18.5 (more )
Note: Triple labeled: red - Fut4; green - Scgb1a1 (assay MGI:6695142); Blue - Calca (assay MGI:6695175).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present 3C left Expressed in secretory precursors.
Specimen 3C Jag1/2 cnull: embryonic day 18.5; Jag1tm1Jlew/Jag1tm1Jlew, Jag2tm2.1Grid/Jag2tm2.1Grid, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Triple labeled: red - Fut4; green - Scgb1a1 (assay MGI:6695142); Blue - Calca (assay MGI:6695175).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present Clusters 3C right Expressed only in secretory precursors tightly associated with the developing neuroepithelial bodies. Nearly absent expression outside the neuroepithelial bodies.
Specimen 3D control: embryonic day 18.5 (more )
Note: Double labeled: red - Fut4; green - Notch1 (assay MGI:6695185).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present 3D right upper Expressed in secretory precursors tightly associated with the developing neuroepithelial bodies.
Specimen 3D Jag1/2 cnull: embryonic day 18.5; Jag1tm1Jlew/Jag1tm1Jlew, Jag2tm2.1Grid/Jag2tm2.1Grid, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: red - Fut4; green - Notch1 (assay MGI:6695185).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present 3D right lower Expressed in secretory precursors tightly associated with the developing neuroepithelial bodies.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory