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Gene Expression Data
Assay Details
Assay
Reference: J:294646 Stupnikov MR, et al., Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation. Elife. 2019 Oct 21;8:e50487
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6695142
Gene symbol: Scgb1a1
Gene name: secretoglobin, family 1A, member 1
Antibody: anti-CC10 (T-18; sc-9772)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2B control: embryonic day 18.5 (more )
Note: Double labeled: green - Scgb1a1; red - Foxj1 (assay MGI:6695145).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present 2B control lower , 2B control upper Expressed in secretory cells.
Specimen 2B Jag1 cnull: embryonic day 18.5; Jag1tm1Jlew/Jag1tm1Jlew, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: green - Scgb1a1; red - Foxj1 (assay MGI:6695145).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present 2B Jag1cKO upper , 2B Jag1cKO lower Reduced expression compared with the control and Jag2cnull.
Specimen 2B Jag2 cnull: embryonic day 18.5; Jag2tm2.1Grid/Jag2tm2.1Grid, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: green - Scgb1a1; red - Foxj1 (assay MGI:6695145).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present 2B Jag2cKO lower , 2B Jag2cKO upper Reduced expression compared with the control.
Specimen 2B Jag1/2 cnull: embryonic day 18.5; Jag1tm1Jlew/Jag1tm1Jlew, Jag2tm2.1Grid/Jag2tm2.1Grid, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: green - Scgb1a1; red - Foxj1 (assay MGI:6695145).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Ambiguous 2B Jag1/2cKO lower , 2B Jag1/2cKO upper Nearly abolished expression compared with the control.
Specimen 3C control: embryonic day 18.5 (more )
Note: Triple labeled: green - Scgb1a1; Blue - Calca (assay MGI:6695175); red - Fut4 (assay MGI:6695148).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present 3C left Expressed in secretory cells.
Specimen 3C Jag1/2 cnull: embryonic day 18.5; Jag1tm1Jlew/Jag1tm1Jlew, Jag2tm2.1Grid/Jag2tm2.1Grid, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Triple labeled: green - Scgb1a1; Blue - Calca (assay MGI:6695175); red - Fut4 (assay MGI:6695148).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Trace 3C right Nearly abolished expression compared with the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory