Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Impg1em1Visu
Name:	interphotoreceptor matrix proteoglycan 1; endonuclease-mediated mutation 1, Visvanathan Ramamurthy
MGI ID:	MGI:6693683
Gene:	Impg1  Location: Chr9:80220612-80347534 bp, - strand  Genetic Position: Chr9, 43.99 cM
Alliance:	Impg1em1Visu page

Strain of Origin:

(C57BL/6 x DBA/2)F1

Allele Type:    Endonuclease-mediated (Null/knockout) Mutation:    Intragenic deletion   Mutation details: CRISPR/cas9 mediated recombination created a 10 nucleotide deletion in exon 2 resulting in a predicted premature termination site in exon 3. Immunohistochemical analysis confirmed the absence of expression in homozygous mice. (J:288311)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Impg1 Mutation:	48 strains or lines available

Original:	J:288311 Salido EM, et al., Proteoglycan IMPG2 Shapes the Interphotoreceptor Matrix and Modulates Vision. J Neurosci. 2020 May 13;40(20):4059-4072
All:	2 reference(s)