Phenotypes associated with this allele
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Impg1em1Visu mutation
(0 available);
any
Impg1 mutation
(48 available)
|
|
|
vision/eye
N |
• no changes in scotopic or photopic ERG responses at 8 months of age
|
|
• the cone specific marker PNA disappears around the outer segments but remains around the inner segments
|
nervous system
|
• the cone specific marker PNA disappears around the outer segments but remains around the inner segments
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Impg1em1Visu mutation
(0 available);
any
Impg1 mutation
(48 available)
Impg2em1Visu mutation
(0 available);
any
Impg2 mutation
(69 available)
|
|
|
vision/eye
N |
• no changes in scotopic or photopic ERG responses or sub-retinal lesions at 8 months of age unlike in mice homozygous for Impg2 allele alone
|
immune system
|
• microglial activation is reduced but not eliminated compared to mice homozygous for Impg2 allele alone
|
nervous system
|
• microglial activation is reduced but not eliminated compared to mice homozygous for Impg2 allele alone
|
hematopoietic system
|
• microglial activation is reduced but not eliminated compared to mice homozygous for Impg2 allele alone
|