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Gene Expression Data
Assay Details
Assay
Reference: J:184934 Lee SH, et al., Runx2 protein stabilizes hypoxia-inducible factor-1alpha through competition with von Hippel-Lindau protein (pVHL) and stimulates angiogenesis in growth plate hypertrophic chondrocytes. J Biol Chem. 2012 Apr 27;287(18):14760-71
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6690657
Gene symbol: Hif1a
Gene name: hypoxia inducible factor 1, alpha subunit
Antibody: anti-HIF-1alpha (clone 54)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 7C WT: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: tibia Present 7C WT Hif-1alpha
Specimen 7C Runx2+/-: embryonic day 15.5; Runx2tm1Mjo/Runx2+ (more )
Structure Level Pattern Image Note
TS23: tibia Present 7C Runx2+/- Hif-1alpha
Specimen 7C Runx2-/-: embryonic day 15.5; Runx2tm1Mjo/Runx2tm1Mjo (more )
Structure Level Pattern Image Note
TS23: tibia Absent 7C Runx2-/- Hif-1alpha
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory