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Gene Expression Data
Assay Details
Assay
Reference: J:117754 Roberts C, et al., Cyp26 genes a1, b1 and c1 are down-regulated in Tbx1 null mice and inhibition of Cyp26 enzyme function produces a phenocopy of DiGeorge Syndrome in the chick. Hum Mol Genet. 2006 Dec 1;15(23):3394-410
Assay type: RNA in situ
MGI Accession ID: MGI:6514305
Gene symbol: Cyp26c1
Gene name: cytochrome P450, family 26, subfamily c, polypeptide 1
Probe: Cyp26c1 cDNA3
Probe preparation: Antisense RNA
Results
Specimen 1F +/+: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch mesenchyme Present 1F +/+
TS15: epibranchial placode Present 1F +/+
Specimen 1F -/-: embryonic day 9.5; Tbx1tm1Bld/Tbx1tm1Bld (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch mesenchyme Present 1F -/- The area of expression is expanded in this mutant.
TS15: epibranchial placode Absent 1F -/-
Specimen 1G +/+: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch mesenchyme Present 1G +/+
TS15: epibranchial placode Present 1G +/+
Specimen 1G -/-: embryonic day 9.5; Tbx1tm1Bld/Tbx1tm1Bld (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch mesenchyme Present 1G -/- The area of expression is expanded in this mutant.
TS15: epibranchial placode Absent 1G -/-
Specimen 1H +/+: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: head mesenchyme Present Regionally restricted 1H +/+ Expression is in peri- and post-otic mesenchyme.
TS15: otocyst Present 1H +/+
TS15: branchial arch endoderm Present Regionally restricted 1H +/+ Expression is caudal.
Specimen 1H -/-: embryonic day 9.5; Tbx1tm1Bld/Tbx1tm1Bld (more )
Structure Level Pattern Image Note
TS15: branchial arch endoderm Absent 1H -/-
TS15: head mesenchyme Absent 1H -/-
TS15: otocyst Absent 1H -/-
Specimen 1I +/+: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: head mesenchyme Present Regionally restricted 1I +/+ Expression is in peri- and post-otic mesenchyme.
TS15: otocyst Present 1I +/+
TS15: branchial arch endoderm Present Regionally restricted 1I +/+ Expression is caudal.
Specimen 1I -/-: embryonic day 9.5; Tbx1tm1Bld/Tbx1tm1Bld (more )
Structure Level Pattern Image Note
TS15: branchial arch endoderm Absent 1I -/-
TS15: head mesenchyme Absent 1I -/-
TS15: otocyst Absent 1I -/-
Specimen 1J: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch endoderm Present 1J Cyp26C1
TS15: 1st branchial arch mesenchyme Present 1J Cyp26C1
Specimen 1K: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: otocyst Present 1K Cyp26C1
TS15: head mesenchyme Present Regionally restricted 1K Cyp26C1 Expression is in the peri-otic mesenchyme.
TS15: 2nd branchial arch mesenchyme Absent 1K Cyp26C1
Specimen 1L: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: head mesenchyme Present Regionally restricted 1L Cyp26C1 Expression is in the post-otic mesenchyme.
TS15: branchial arch endoderm Present 1L Cyp26C1
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory