Gene Expression Data
Assay Details
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Assay
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Reference:
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J:117754
Roberts C, et al., Cyp26 genes a1, b1 and c1 are down-regulated in Tbx1 null mice and inhibition of Cyp26 enzyme function produces a phenocopy of DiGeorge Syndrome in the chick. Hum Mol Genet. 2006 Dec 1;15(23):3394-410
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6514304
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Gene symbol:
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Cyp26b1
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Gene name:
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cytochrome P450, family 26, subfamily b, polypeptide 1
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Results
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Specimen
1D +/+:
embryonic day 9.5
(more  )
Specimen
1D +/+:
(close  )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
1D -/-:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Tbx1tm1Bld/Tbx1tm1Bld
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: branchial arch endoderm |
Present |
Regionally restricted |
1D -/-
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Expression is absent in the caudal pharyngeal endoderm.
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| TS15: branchial arch ectoderm |
Present |
Regionally restricted |
1D -/-
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In this mutant there is an anterior shift in ectodermal expression.
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| TS15: future hindbrain |
Strong |
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1D -/-
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Expression in the hindbrain of this mutant is the same as in wild-type.
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Specimen
1E +/+:
embryonic day 9.5
(more )
Specimen
1E +/+:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Embedding:
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Paraffin
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Specimen
1E -/-:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Tbx1tm1Bld/Tbx1tm1Bld
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: branchial arch endoderm |
Present |
Regionally restricted |
1E -/-
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Expression is absent in the caudal pharyngeal endoderm.
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| TS15: branchial arch ectoderm |
Present |
Regionally restricted |
1E -/-
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In this mutant there is an anterior shift in ectodermal expression.
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Analysis Tools