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Gene Expression Data
Assay Details
Assay
Reference: J:280280 Rutledge EA, et al., Morphogenesis of the kidney and lung requires branch-tip directed activity of the Adamts18 metalloprotease. Dev Biol. 2019 Oct 15;454(2):156-169
Assay type: RNA in situ
MGI Accession ID: MGI:6512065
Gene symbol: Fgf10
Gene name: fibroblast growth factor 10
Probe: Mm-Fgf10 (446371)
Probe preparation: Antisense
Visualized with: Chromogenic
Assay notes: RNAscope assay
Results
Specimen 10C: embryonic day 12.5 (more )
Note: Double labeled: green - Fgf10; red - Bmp4 (assay MGI:6512066)
Structure Level Pattern Image Note
TS20: ureteric tip Trace 10C
TS20: ureteric trunk Trace 10C
TS20: metanephros Present Regionally restricted 10C Nearly all expression is seen in non-uteric bud cells.
Specimen 10D: embryonic day 12.5; Adamts18tm1(KOMP)Vlcg/Adamts18tm1(KOMP)Vlcg (more )
Note: Double labeled: green - Fgf10; red - Bmp4 (assay MGI:6512066)
Structure Level Pattern Image Note
TS20: ureteric tip Trace 10D The number of transcripts per cell is the same in the mutant as in wild type.
TS20: ureteric trunk Trace 10D The number of transcripts per cell is the same in the mutant as in wild type.
TS20: metanephros Present Regionally restricted 10D Nearly all expression is seen in non-uteric bud cells. The number of transcripts per cell is the same in the mutant as in wild type.
Specimen 10G: embryonic day 12.5 (more )
Note: Double labeled: green - Fgf10; red - Bmp4 (assay MGI:6512066)
Structure Level Pattern Image Note
TS20: lung Present Regionally restricted 10G Nearly all expression is seen in non-epithelial cells.
Specimen 10H: embryonic day 12.5; Adamts18tm1(KOMP)Vlcg/Adamts18tm1(KOMP)Vlcg (more )
Note: Double labeled: green - Fgf10; red - Bmp4 (assay MGI:6512066)
Structure Level Pattern Image Note
TS20: lung Present Regionally restricted 10H Nearly all expression is seen in non-epithelial cells. The number of transcripts per cell is the same in the mutant as in wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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