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Gene Expression Data
Assay Details
Assay
Reference: J:291094 Sheikh BN, et al., Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature. Nat Cell Biol. 2020 Jul;22(7):828-841
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6511318
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Results
Specimen 6f Nes-Cre T/+: embryonic day 14.5; Tg(Nes-cre)1Kln/0 (more )
Note: Embedded in hydrogel monomer solution (A4P0; 4% acrylamide and 0.25% photo-initiator.
Structure Level Pattern Image Note
TS22: brain vascular element Present 6f Nes-Cre T/+
Specimen 6f Nes-Cre T/+ inset: embryonic day 14.5; Tg(Nes-cre)1Kln/0 (more )
Note: Embedded in hydrogel monomer solution (A4P0; 4% acrylamide and 0.25% photo-initiator.
Structure Level Pattern Image Note
TS22: forebrain vascular element Present 6f Nes-Cre T/+ inset
Specimen 6f Mof nKO: embryonic day 14.5; Kat8tm1.2Avo/Kat8tm1.2Avo, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Embedded in hydrogel monomer solution (A4P0; 4% acrylamide and 0.25% photo-initiator.
Structure Level Pattern Image Note
TS22: forebrain vascular element Present 6f Mof-nKO Authors report no signficant changes in vascularization of the brain or zonation of endothelial cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
MGI 6.24 		The Jackson Laboratory