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Gene Expression Data
Assay Details
Assay
Reference: J:160146 Rowan S, et al., Precise temporal control of the eye regulatory gene Pax6 via enhancer-binding site affinity. Genes Dev. 2010 May 15;24(10):980-5
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6502089
Gene symbol: Foxe3
Gene name: forkhead box E3
Antibody: anti-Foxe3
Detection system: Cy3
Results
Specimen 1B Prep1+/+ Foxe3: embryonic day 12.5 (more )
Note: Double labeled: red - Foxe3; green - Cryg (assay MGI:6502088).
Structure Level Pattern Image Note
TS20: lens vesicle epithelium Present 1B Prep1+/+ Foxe3/g-crystallin Expression in lens epithelial cells.
Specimen 1B Prep1i/- Foxe3: embryonic day 12.5; Pknox1Gt(OST71835)Lex/Pknox1tm1Ngc (more )
Note: Double labeled: red - Foxe3; green - Cryg (assay MGI:6502088).
Structure Level Pattern Image Note
TS20: lens primordium Absent 1B Prep1i/- Foxe3/g-crystallin Authors report that lens epithelial cells did not form.
Specimen 1C E9.5 Prep1+/+ Foxe3: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: lens pre-placode Present Regionally restricted 1C E9.5 Prep1+/+ Foxe3 Expression in presumptive lens epithelium.
Specimen 1C E9.5 Prep1i/- Foxe3: embryonic day 9.5; Pknox1Gt(OST71835)Lex/Pknox1tm1Ngc (more )
Structure Level Pattern Image Note
TS15: lens primordium Absent 1C E9.5 Prep1i/- Foxe3 Authors report Prep1i/- mice do not initiate Foxe3 expression.
Specimen 1C E10.5 Prep1+/+ Foxe3: embryonic day 10.5; Pax6Sey-Neu/Pax6Sey-Neu (more )
Structure Level Pattern Image Note
TS17: lens pit Present Regionally restricted 1C E10.5 Prep1+/+ Foxe3 Expression in presumptive lens epithelium.
Specimen 1C E10.5 Prep1i/- Foxe3: embryonic day 10.5; Pknox1Gt(OST71835)Lex/Pknox1tm1Ngc (more )
Structure Level Pattern Image Note
TS17: lens primordium Absent 1C E10.5 Prep1i/- Foxe3 Authors report Prep1i/- mice do not initiate Foxe3 expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory