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Gene Expression Data
Assay Details
Assay
Reference: J:150043 Bush JO, et al., Ephrin-B1 regulates axon guidance by reverse signaling through a PDZ-dependent mechanism. Genes Dev. 2009 Jul 1;23(13):1586-99
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6500860
Gene symbol: Efnb1
Gene name: ephrin B1
Results
Specimen E13.5 not shown: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Strong Widespread Strong expression throughout cortex between E13.5 and E18.5.
Specimen E18.5 not shown: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Strong Widespread Strong expression throughout cortex between E13.5 and E18.5.
TS26: cerebral cortex intermediate zone Present Expression within ventricular and intermediate zones.
TS26: cerebral cortex ventricular layer Present Expression within ventricular and intermediate zones.
TS26: cerebral hemisphere white matter Present Regionally restricted Expression in radial glia.
Specimen 6C/D: embryonic day 18.0 (more )
Note: Triple labeled: red - Efnb1; green - L1cam (assay MGI:6500854); blue - Gfap (assay MGI:6500859).
Structure Level Pattern Image Note
TS26: corpus callosum Present Regionally restricted 6C , 6D Co-expression with L1cam in axons of corpus callosum.
TS26: indusium griseum Absent 6D , 6C No co-expression with Gfap in induseum griseum.
TS26: telencephalon pia mater Strong Regionally restricted 6D , 6C Strong expression within interhemispheric pial membrane cells.
Specimen 6G/H: embryonic day 18.0 (more )
Note: Triple labeled: red - Efnb1; green - L1cam (assay MGI:6500854); blue - Gfap (assay MGI:6500859).
Structure Level Pattern Image Note
TS26: telencephalon subventricular zone Present 6H , 6G
TS26: cerebral hemisphere white matter Present Regionally restricted 6H , 6G Expression in some but not all cells within glial wedge.
Specimen 6S/T: embryonic day 17.5; Efnb1tm3.2Sor/Efnb1tm3.2Sor (more )
Note: Triple labeled: red - Efnb1; green - L1cam (assay MGI:6500854); blue - Gfap (assay MGI:6500859).
Structure Level Pattern Image Note
TS25: telencephalon ventricular layer Present 6S , 6T Author report normal expression within ventricular zone.
TS25: corpus callosum Present Regionally restricted 6S , 6T Co-expression with L1cam within non-crossing corpus callosum axons.
TS25: indusium griseum Absent 6S , 6T No expression within mislocalized Gfap-expressing induseum griseum cells.
TS25: telencephalon pia mater Strong Regionally restricted 6T , 6S Strong expression within interhemispheric pial membrane cells.
Specimen S4B/C: embryonic day 16.5 (more )
Note: Double labeled: green - Efnb1; red - Gfap (assay MGI:6500859).
Structure Level Pattern Image Note
TS24: telencephalon subventricular zone Strong S4C , S4B Strongest expression within subventricular zone.
Specimen S4E/F: embryonic day 16.5 (more )
Note: Double labeled: green - Efnb1; red - Gfap (assay MGI:6500859).
Structure Level Pattern Image Note
TS24: corpus callosum Present S4F , S4E Expression also detectable within axons of corpus callosum.
Specimen S4H/I: embryonic day 16.5 (more )
Note: Double labeled: green - Efnb1; red - Gfap (assay MGI:6500859).
Structure Level Pattern Image Note
TS24: cerebral hemisphere white matter Present Regionally restricted S4H , S4I Expression within many cells of glial wedge.
Specimen S4K/L: embryonic day 16.5; Efnb1tm4.2Sor/Efnb1tm4.2Sor (more )
Note: Double labeled: green - Efnb1; red - Gfap (assay MGI:6500859).
Structure Level Pattern Image Note
TS24: cerebral hemisphere white matter Present Regionally restricted S4K , S4L Authors report expression is indistinguishable from wild type.
TS24: corpus callosum Present Regionally restricted S4K , S4L Authors report expression is indistinguishable from wild type.
TS24: telencephalon subventricular zone Present Regionally restricted S4K , S4L Authors report expression is indistinguishable from wild type.
Specimen S5B/D: embryonic day 17.5 (more )
Note: Triple labeled: blue - Efnb1; green - L1cam (assay MGI:6500854); red - Rgs3 (assay MGI:6500864).
Structure Level Pattern Image Note
TS25: corpus callosum Present S5B , S5D
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory