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Gene Expression Data
Assay Details
Assay
Reference: J:283401 Masgutova G, et al., Pou2f2 Regulates the Distribution of Dorsal Interneurons in the Mouse Developing Spinal Cord. Front Mol Neurosci. 2019;12:263
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6491252
Gene symbol: Pou2f2
Gene name: POU domain, class 2, transcription factor 2
Results
Specimen 2A: embryonic day 10.5 (more )
Note: Double labeled: red - Pou2f2; green - Foxd3 (assay MGI:6491253).
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 2A Expression in post-mitotic Foxd3-expressing dl2 interneurons, particularly in ventral part of population, at E10.5.
Specimen 2B: embryonic day 10.5; Onecut1tm1Flem/Onecut1tm1Flem, Onecut2tm1Flem/Onecut2tm1Flem (more )
Note: Double labeled: red - Pou2f2; green - Foxd3 (assay MGI:6491253).
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 2B Stronger expression in Foxd3-expressing dl2 interneurons than in controls at all stages.
Specimen 2C: embryonic day 11.5 (more )
Note: Double labeled: red - Pou2f2; green - Foxd3 (assay MGI:6491253).
Structure Level Pattern Image Note
TS19: future spinal cord Present Regionally restricted 2C Decreased expression in post-mitotic Foxd3-expressing dl2 interneurons, particularly in ventral part of population, at E11.5.
Specimen 2D: embryonic day 11.5; Onecut1tm1Flem/Onecut1tm1Flem, Onecut2tm1Flem/Onecut2tm1Flem (more )
Note: Double labeled: red - Pou2f2; green - Foxd3 (assay MGI:6491253).
Structure Level Pattern Image Note
TS19: future spinal cord Present Regionally restricted 2D Stronger expression in Foxd3-expressing dl2 interneurons than in controls at all stages.
Specimen 2E: embryonic day 12.5 (more )
Note: Triple labeled: red - Pou2f2; green - Foxd3 (assay MGI:6491253); blue - Brn3a (Pou4f1 assay MGI:6491254).
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted 2E Expression almost absent in Foxd3-expressing dl2 interneurons at E12.5.
Specimen 2F: embryonic day 12.5; Onecut1tm1Flem/Onecut1tm1Flem, Onecut2tm1Flem/Onecut2tm1Flem (more )
Note: Triple labeled: red - Pou2f2; green - Foxd3 (assay MGI:6491253); blue - Brn3a (Pou4f1 assay MGI:6491254).
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted 2F Stronger expression in Foxd3-expressing dl2 interneurons than in controls at all stages.
Specimen 3A: embryonic day 10.5 (more )
Note: Double labeled: red - Pou2f2; green - Isl1 (assay MGI:6491255).
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 3A Expression in ventral part of post-mitotic Isl1-expressing dl3 interneurons from E10.5
Specimen 3B: embryonic day 10.5; Onecut1tm1Flem/Onecut1tm1Flem, Onecut2tm1Flem/Onecut2tm1Flem (more )
Note: Double labeled: red - Pou2f2; green - Isl1 (assay MGI:6491255).
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 3B Stronger expression in Isl1-expressing dl3 interneurons than in controls at all stages.
Specimen 3C: embryonic day 11.5 (more )
Note: Double labeled: red - Pou2f2; green - Isl1 (assay MGI:6491255).
Structure Level Pattern Image Note
TS19: future spinal cord Present Regionally restricted 3C Expression in ventral part of post-mitotic Isl1-expressing dl3 interneurons.
Specimen 3D: embryonic day 11.5; Onecut1tm1Flem/Onecut1tm1Flem, Onecut2tm1Flem/Onecut2tm1Flem (more )
Note: Double labeled: red - Pou2f2; green - Isl1 (assay MGI:6491255).
Structure Level Pattern Image Note
TS19: future spinal cord Present Regionally restricted 3D Stronger expression in Isl1-expressing dl3 interneurons than in controls at all stages.
Specimen 3E: embryonic day 12.5 (more )
Note: Double labeled: red - Pou2f2; green - Isl1 (assay MGI:6491255).
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted 3E Expression in ventral part of post-mitotic Isl1-expressing dl3 interneurons.
Specimen 3F: embryonic day 12.5; Onecut1tm1Flem/Onecut1tm1Flem, Onecut2tm1Flem/Onecut2tm1Flem (more )
Note: Double labeled: red - Pou2f2; green - Isl1 (assay MGI:6491255).
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted 3F Stronger expression in Isl1-expressing dl3 interneurons than in controls at all stages.
Specimen 4A: embryonic day 10.5 (more )
Note: Double labeled: red - Pou2f2; green - Lmx1b (assay MGI:6491256).
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 4A Expression in most Lmx1b-expressing dl5 interneurons at E10.5, restricted to ventral part of population.
Specimen 4B: embryonic day 10.5; Onecut1tm1Flem/Onecut1tm1Flem, Onecut2tm1Flem/Onecut2tm1Flem (more )
Note: Double labeled: red - Pou2f2; green - Lmx1b (assay MGI:6491256).
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 4B Stronger expression in Lmx1b-expressing dl5 interneurons than in controls at all stages.stages.studied.
Specimen 4D: embryonic day 11.5 (more )
Note: Double labeled: red - Pou2f2; green - Lmx1b (assay MGI:6491256).
Structure Level Pattern Image Note
TS19: future spinal cord Present Regionally restricted 4D Expression in most Lmx1b-expressing dl5 interneurons, restricted to ventral part of population.
Specimen 4E: embryonic day 11.5; Onecut1tm1Flem/Onecut1tm1Flem, Onecut2tm1Flem/Onecut2tm1Flem (more )
Note: Double labeled: red - Pou2f2; green - Lmx1b (assay MGI:6491256).
Structure Level Pattern Image Note
TS19: future spinal cord Present Regionally restricted 4E Stronger expression in Lmx1b-expressing dl5 interneurons than in controls at all stages.
Specimen 4G: embryonic day 12.5 (more )
Note: Double labeled: red - Pou2f2; green - Dmrt3 (assay MGI:6491257).
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted 4G Expression in Dmrt3-expressing dl6 interneurons.
Specimen 4H: embryonic day 12.5; Onecut1tm1Flem/Onecut1tm1Flem, Onecut2tm1Flem/Onecut2tm1Flem (more )
Note: Double labeled: red - Pou2f2; green - Dmrt3 (assay MGI:6491257).
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted 4H Stronger expression in Dmrt3-expressing dl6 interneurons than in controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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