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Gene Expression Data
Assay Details
Assay
Reference: J:294694 Furusawa T, et al., Down-regulation of nucleosomal binding protein HMGN1 expression during embryogenesis modulates Sox9 expression in chondrocytes. Mol Cell Biol. 2006 Jan;26(2):592-604
Assay type: RNA in situ
MGI Accession ID: MGI:6490496
Gene symbol: Hmgn1
Gene name: high mobility group nucleosomal binding domain 1
Probe: Hmgn1 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1Aa: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: embryo Strong 1Aa Strong expression is seen in the epiblast.
TS11: extraembryonic ectoderm Weak 1Aa
TS11: ectoplacental cone Absent 1Aa
Specimen 1Ab: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: embryo Strong Widespread 1Ab
TS13: heart Ambiguous 1Ab The heart lacks the strong expression seen elsewhere in the embryo.
Specimen 1Ac: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo Strong Widespread 1Ac
TS15: heart Ambiguous 1Ac The heart lacks the strong expression seen elsewhere in the embryo.
Specimen 1Ad: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Strong Widespread 1Ad
TS17: forelimb bud mesenchyme Strong 1Ad The distal portion of the mesenchyme is one of the areas of strongest expression.
TS17: hindlimb bud mesenchyme Strong 1Ad The distal portion of the mesenchyme is one of the areas of strongest expression.
TS17: branchial arch Strong 1Ad This is one of the areas of strongest expression.
TS17: tail Strong 1Ad This is one of the areas of strongest expression.
TS17: heart Absent 1Ad
Specimen 1Ae: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Strong 1Ae
TS19: hindlimb bud mesenchyme Strong 1Ae
TS19: tail Strong 1Ae
TS19: heart Absent 1Ae
Specimen 1Af: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb mesenchyme Strong 1Af
TS20: hindlimb mesenchyme Strong 1Af
TS20: tail Strong 1Af
TS20: heart Absent 1Af
Specimen 1Ag: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: forelimb mesenchyme Present 1Ag
TS21: hindlimb mesenchyme Present 1Ag
TS21: tail Present 1Ag
Specimen 1Ah: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: forelimb mesenchyme Present 1Ah
TS22: hindlimb mesenchyme Present 1Ah
TS22: tail Present 1Ah
Specimen 3A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud Strong Regionally restricted 3A Expression is seen in a borad anterior and distal region; it was down-regulated in the proximal region.
Specimen 3C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: handplate mesenchyme Present Regionally restricted 3C Expression starts to be restricted to the interdigital mesenchyme; it is down-regulated in the future digit region.
Specimen 3E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb interdigital region Present 3E
Specimen 3G: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: forelimb interdigital region mesenchyme Present Regionally restricted 3G Expression begins to weaken in the interdigital mesenchyme; it is restricted to perichondrium.
Specimen 3I: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: forelimb interdigital region mesenchyme Present Regionally restricted 3I Expression is localized to the perichondrium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory