Tyr RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:65992 Surace EM, et al., Expression pattern of the ocular albinism type 1 (Oa1) gene in the murine retinal pigment epithelium. Invest Ophthalmol Vis Sci. 2000 Dec;41(13):4333-7
Assay type:	RNA in situ
MGI Accession ID:	MGI:6489592
Gene symbol:	Tyr
Gene name:	tyrosinase

Probe:	Tyr probe3
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

Specimen E9.5 not shown: embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: optic vesicle	Absent

Specimen 3C: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: optic cup	Present	Regionally restricted	3C	Expression restricted to dorsal part of optic cup. Expression only in external layer fated to become retinal pigment epithelium.

Specimen 3D: embryonic day 11.5 (more

)

Structure	Level	Pattern	Image	Note
TS19: retina epithelium	Present	Regionally restricted	3D	Expression in all cells of extenal layer of optic cup. Expression expanded from dorsal to ventral side.

Specimen 4C: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: pigmented retinal epithelium	Present		4C
TS26: ciliary body	Present		4C	Expression extended to ciliary body.

Specimen 4D: postnatal day 0 (more

)

Structure	Level	Pattern	Image	Note
TS27: pigmented retinal epithelium	Present		4D

Specimen adult not shown: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: pigmented retinal epithelium	Present

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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