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Gene Expression Data
Assay Details
Assay
Reference: J:63842 Cheung M, et al., Roles of Sox4 in central nervous system development. Brain Res Mol Brain Res. 2000 Jun 23;79(1-2):180-91
Assay type: RNA in situ
MGI Accession ID: MGI:6488420
Gene symbol: Sox11
Gene name: SRY (sex determining region Y)-box 11
Probe: Sox11 cDNA11
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forebrain Present 1E
TS17: future spinal cord Present 1E
TS17: limb Present 1E
TS17: midbrain Present 1E

Specimen 1F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present 1F
TS17: limb Present 1F
TS17: future spinal cord Present Regionally restricted 1F Expression is in two stripes.

Specimen 2C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted 2C Expression is in the sub-ventricular zone in the ventral region.

Specimen 2F: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: neural tube lateral wall Weak Regionally restricted 2F Expression is low in the ventricular zone with scattered higher expressing cells.

Specimen 2I: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: spinal cord lateral wall Strong Regionally restricted 2I Expression is in the sub-ventricular zone.
TS20: spinal cord ventricular layer Weak 2I Expression is low in the ventricular zone with scattered higher expressing cells.

Specimen 2L: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: spinal cord lateral wall Present 2L

Specimen 2O: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: spinal cord lateral wall Weak 2O

Specimen 3B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: telencephalon Strong Regionally restricted 3B Expression is in the primordial plexiform layer.

Specimen 3D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: main olfactory bulb layer Strong Regionally restricted 3D Expression is in the primordial plexiform layer.

Specimen 3F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex subventricular zone Present 3F
TS24: cortical plate Weak 3F

Specimen 3H: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cortical plate Strong Regionally restricted 3H Expression is in the upper cortical plate.

Specimen 3J: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Weak Regionally restricted 3J Expression is in the cortical plate and is absent in the deeper layer.

Specimen 4B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: diencephalon Present Regionally restricted 4B Expression is in the subventricular zone.

Specimen 4D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: thalamus Present Regionally restricted 4D Expression is in the differentiating region.

Specimen 4F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: thalamus Trace 4F

Specimen 5B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hippocampus Present Regionally restricted 5B Expression is in the hippocampal inferior band and in the developing CA1 and CA3 regions.
TS24: dentate gyrus Present Regionally restricted 5B Expression is in a population of cells migrating from the primary dentate neuroepithelium.

Specimen 5D: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: CA1 pyramidal cell layer Weak 5D
TS27: dentate gyrus Present Regionally restricted 5D Expression is in the migrating granule cell precursors.

Specimen 5F: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: dentate gyrus granule cell layer Present 5F

Specimen 6B: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cerebellum external granule cell layer Strong 6B
TS27: cerebellum ventricular layer Weak 6B
TS27: cerebellum layer Present Regionally restricted 6B Expression is in a broad region immediately below the external granule layer.

Specimen 6E: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Strong Regionally restricted 6F , 6E Expression is strong in the deep layer and at lower levels in the superficial layer.
TS28: cerebellum internal granule cell layer Trace 6F , 6E
TS28: cerebellum white matter Present 6E , 6F

Specimen 7C: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: spinal cord lateral wall Strong Regionally restricted 7C Expression is in the sub-ventricular zone with weak expression in the more peripheral region.

Specimen 7D: embryonic day 12.0; Sox4tm1Cle/Sox4tm1Cle (more )
Structure Level Pattern Image Note
TS20: spinal cord lateral wall Strong Regionally restricted 7D Expression in this mutant is the same as in wild-type.

Specimen 8C: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: forebrain Present 8C

Specimen 8D: embryonic day 12.0; Sox4tm1Cle/Sox4tm1Cle (more )
Structure Level Pattern Image Note
TS20: forebrain Present 8D Expression in this mutant is the same as in wild-type.

Specimen not shown E8.5: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: neural tube Strong

Specimen not shown P7: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: hippocampus Absent
TS28: spinal cord lateral wall Absent


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory