Six2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:88686 Wellik DM, et al., Hox11 paralogous genes are essential for metanephric kidney induction. Genes Dev. 2002 Jun 1;16(11):1423-32
Assay type:	RNA in situ
MGI Accession ID:	MGI:6488193
Gene symbol:	Six2
Gene name:	sine oculis-related homeobox 2

Probe:	Six2 probe11
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

5H ©

Specimen 5H: embryonic day 10.5; Hoxd11^tm1Mrc/Hoxd11⁺ (more

)

Structure	Level	Pattern	Image	Note
TS17: metanephric mesenchyme	Present	Regionally restricted	5H	Expression in metanephric blastema.

5I ©

Specimen 5I: embryonic day 11.0; Hoxa11^tm1Mrc/Hoxa11^tm1Mrc, Hoxc11^tm1Mrc/Hoxc11⁺, Hoxd11^tm1Mrc/Hoxd11^tm1Mrc (more

)

Structure	Level	Pattern	Image	Note
TS18: metanephric mesenchyme	Trace		5I	Drastic reduction in expression.
TS18: ureteric bud	Absent		5I

5J ©

Specimen 5J: embryonic day 10.5; Hoxa11^tm1Mrc/Hoxa11^tm1Mrc, Hoxc11^tm1Mrc/Hoxc11^tm1Mrc, Hoxd11^tm1Mrc/Hoxd11^tm1Mrc (more

)

Structure	Level	Pattern	Image	Note
TS17: metanephric mesenchyme	Absent		5J

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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