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Gene Expression Data
Assay Details
Assay
Reference: J:289438 Kischel A, et al., Ephrin-B2 paces neuronal production in the developing neocortex. BMC Dev Biol. 2020 May 13;20(1):12
Assay type: RNA in situ
MGI Accession ID: MGI:6488150
Gene symbol: Efnb2
Gene name: ephrin B2
Probe: Efnb2 probe5
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1A E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: telencephalon Strong 1A E10.5 Strong expression in neuroepithelial cells.
Specimen 1A E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: neocortex Present Regionally restricted 1A E13.5 Expression in neural progenitors.
TS21: cortical plate Present Graded 1A E13.5 Expression in high-lateral to low-medial gradient.
Specimen 1A E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: neocortex Present Graded 1A E16.5 Low expression in progenitors and deep neurons; high expression in upper layer neurons.
Specimen 1A E18.5: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: neocortex Present Graded 1A E18.5 Low expression in progenitors and deep neurons; high expression in upper layer neurons.
Specimen S1A Control: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: telencephalon Present S1A Control
Specimen S1A efnb2lox/lox:NesCre: embryonic day 11.5; Efnb2tm2Sor/Efnb2tm2Sor (more )
Structure Level Pattern Image Note
TS19: telencephalon Absent S1A efnb2lox/lox;NesCre
Specimen S1B Control: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: neocortex Present S1B Control
Specimen S1B efnb2lox/lox/NexCre: embryonic day 13.5; Efnb2tm4Kln/Efnb2tm4Kln, Neurod6tm1(cre)Kan/Neurod6+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: neocortex Present S1B efnb2lox/lox;NexCre
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory