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Gene Expression Data
Assay Details
Assay
Reference: J:173601 Poulsen RR, et al., The Sphingosine-1-phospate receptor 1 mediates S1P action during cardiac development. BMC Dev Biol. 2011;11:37
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6480057
Gene symbol: Fn1
Gene name: fibronectin 1
Antibody: anti-fibronectin
Detection system: Alexa Fluor 488
Results
Specimen 8A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: atrioventricular endocardial cushion Strong 8A Strong expression in outflow tractand atrioventricular canal cushions.
TS20: outflow tract endocardial cushion Strong 8A Strong expression in outflow tractand atrioventricular canal cushions.
TS20: trabecular myocardium Present Widespread 8A Expression throughout ventricular myocardium and trabeculae.
TS20: ventricle cardiac muscle Present Widespread 8A Expression throughout ventricular myocardium and trabeculae.
TS20: visceral pericardium Strong 8A Strong expression in epicardial layer.
Specimen 8B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: atrioventricular endocardial cushion Strong 8B Strong expression in atrioventricular canal cushions.
TS20: trabecular myocardium Present Widespread 8B Strong expression in epicardial layer.
TS20: ventricle cardiac muscle Present Widespread 8B Strong expression in epicardial layer.
Specimen 8C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: trabecular myocardium Present Widespread 8C Expression throughout ventricular myocardium
TS20: ventricle cardiac muscle Present Widespread 8C Expression throughout ventricular myocardium
TS20: visceral pericardium Strong 8C Strong expression in epicardial layer.
Specimen 8D: embryonic day 12.5; S1pr1tm1Rlp/S1pr1tm1Rlp (more )
Structure Level Pattern Image Note
TS20: atrioventricular endocardial cushion Weak 8D Reduced expression in outflow trReduced expression in outflow tract. and atrioventricular canal cushions.act. and atrioventricular canal cushions.
TS20: outflow tract endocardial cushion Weak 8D Reduced expression in outflow trReduced expression in outflow tract. and atrioventricular canal cushions.act. and atrioventricular canal cushions.
TS20: trabecular myocardium Weak Regionally restricted 8D Reduced expression surrounding myocardial trabecular cells.
TS20: ventricle cardiac muscle Weak Regionally restricted 8D Reduced expression surrounding myocardial trabecular cells.
TS20: visceral pericardium Present Regionally restricted 8D Expression in epicardial layer that is more disorganized compared to wild-type heart.
Specimen 8E: embryonic day 12.5; S1pr1tm1Rlp/S1pr1tm1Rlp (more )
Structure Level Pattern Image Note
TS20: atrioventricular endocardial cushion Weak 8E Reduced expression in atrioventricular canal cushions.
TS20: trabecular myocardium Weak Regionally restricted 8E Reduced expression surrounding myocardial trabecular cells.
TS20: ventricle cardiac muscle Weak Regionally restricted 8E Reduced expression surrounding myocardial trabecular cells.
TS20: visceral pericardium Present Regionally restricted 8E Expression in epicardial layer that is more disorganized compared to wild-type heart.
Specimen 8F: embryonic day 12.5; S1pr1tm1Rlp/S1pr1tm1Rlp (more )
Structure Level Pattern Image Note
TS20: trabecular myocardium Weak Regionally restricted 8F Reduced expression surrounding myocardial trabecular cells.
TS20: ventricle cardiac muscle Weak Regionally restricted 8F Reduced expression surrounding myocardial trabecular cells.
TS20: visceral pericardium Present Regionally restricted 8F Expression in epicardial layer that is more disorganized compared to wild-type heart.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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