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Gene Expression Data
Assay Details
Assay
Reference: J:290889 Sreenivasan R, et al., Altered SOX9 genital tubercle enhancer region in hypospadias. J Steroid Biochem Mol Biol. 2017 Jun;170:28-38
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6479870
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Antibody: Anti-Sox9
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: genital tubercle Present Regionally restricted 5_Sox9 center Expression was detected in the corpus cavernosa.
TS23: preputial gland of male Present Regionally restricted 5_Sox9 center , 5_Sox9 left
TS23: surface ectoderm of genital tubercle Present Regionally restricted 5_Sox9 left , 5_Sox9 center Expression was detected in the ventral surface ectoderm.
TS23: urethral plate epithelium Present 5_Sox9 right , 5_Sox9 center
Specimen not shown: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: genital tubercle Present
Specimen 7 +/+;Sox9flox/flox control left: embryonic day 15.5; Sox9tm1Gsr/Sox9tm1Gsr (more )
Structure Level Pattern Image Note
TS23: urethral plate epithelium Present 7_+/+;Sox9flox/flox Urethral plate epithelium
Specimen 7 Shh-Cre/+;Sox9flox/flox mutant left: embryonic day 15.5; Sox9tm1Gsr/Sox9tm1Gsr, Shhtm3(cre)Chg/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: urethral plate epithelium Absent 7_Shh-Cre/+;Sox9flox/flox Urethral plate epithelium
Specimen 7 +/+;Sox9flox/flox mutant right: embryonic day 15.5; Sox9tm1Gsr/Sox9tm1Gsr (more )
Structure Level Pattern Image Note
TS23: preputial gland Present 7_+/+;Sox9flox/flox Preputial swelling
TS23: surface ectoderm of genital tubercle Present Regionally restricted 7_+/+;Sox9flox/flox Preputial swelling Expression was detected in the ventral surface ectoderm.
Specimen 7 Shh-Cre/+;Sox9flox/flox mutant right: embryonic day 15.5; Sox9tm1Gsr/Sox9tm1Gsr, Shhtm3(cre)Chg/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: preputial gland Absent 7_Shh-Cre/+;Sox9flox/flox Preputial swelling
TS23: surface ectoderm of genital tubercle Absent 7_Shh-Cre/+;Sox9flox/flox Preputial swelling Expression was successfully ablated in the mutant ventral surface ectoderm.
Specimen not shown: embryonic day 15.5; Sox9tm1Gsr/Sox9tm1Gsr (more )
Structure Level Pattern Image Note
TS23: genital tubercle Present Regionally restricted Expression was detected in the corpus cavernosa.
Specimen not shown: embryonic day 15.5; Sox9tm1Gsr/Sox9tm1Gsr, Shhtm3(cre)Chg/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: genital tubercle Present Regionally restricted Expression was detected in the corpus cavernosa, as in control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/31/2026
MGI 6.24 		The Jackson Laboratory