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Gene Expression Data
Assay Details
Assay
Reference: J:35772 Gale NW, et al., Elk-L3, a novel transmembrane ligand for the Eph family of receptor tyrosine kinases, expressed in embryonic floor plate, roof plate and hindbrain segments. Oncogene. 1996 Sep 19;13(6):1343-52
Assay type: RNA in situ
MGI Accession ID: MGI:6479727
Gene symbol: Efnb3
Gene name: ephrin B3
Probe: Elk-L3 cDNA3
Probe preparation: Antisense RNA
Results
Specimen 5A: embryonic day 8.5 (more )
Note: 8 somite-stage embryo
Structure Level Pattern Image Note
TS13: rhombomere 2 Weak 5A
TS13: rhombomere 4 Weak 5A
TS13: future prosencephalon neural fold Present 5A
TS13: future hindbrain Present Regionally restricted 5A Expression is seen in the caudal hindbrain.
TS13: future spinal cord Present Regionally restricted 5A Expression is seen in the rostral spinal cord region.
Specimen 5D: embryonic day 8.5 (more )
Note: 11-12 somite-stage embryo
Structure Level Pattern Image Note
TS13: rhombomere 1 Present Widespread 5D
TS13: rhombomere 2 Present Regionally restricted 5D Expression is seen in the caudal boundary and ventral part of the rhombomere.
TS13: rhombomere 4 Present Regionally restricted 5D Expression is restricted to the boundaries of the rhombomere.
TS13: rhombomere 5 Absent 5D
TS13: future hindbrain Present Regionally restricted 5D Expression is seen in the rostral spinal cord/caudal hindbrain up to the rhombomere 5/6 boundary.
TS13: future spinal cord Present Regionally restricted 5D Expression is seen in the rostral spinal cord/caudal hindbrain up to the rhombomere 5/6 boundary.
TS13: future midbrain Present Regionally restricted 5D Expression is seen in the ventral region.
TS13: future prosencephalon Present Regionally restricted 5D Expression is seen in the ventral region.
Specimen 5E: embryonic day 8.5 (more )
Note: 11-12 somite-stage embryo
Structure Level Pattern Image Note
TS13: rhombomere 2 Present Regionally restricted 5E Expression is seen in the caudal boundary and ventral part of the rhombomere.
TS13: rhombomere 4 Present Regionally restricted 5E Expression is restricted to the boundaries of the rhombomere.
TS13: rhombomere Present 5E Expression is seen in rhombomere 6.
Specimen 5F: embryonic day 8.5 (more )
Note: 12 somite-stage embryo
Structure Level Pattern Image Note
TS13: future prosencephalon Present Regionally restricted 5F Expression is seen in the ventral forebrain.
TS13: future midbrain Present Regionally restricted 5F Expression is seen in the ventral midbrain.
TS13: future hindbrain Present 5F
Specimen 5I: embryonic day 10.0 (more )
Note: rostral spinal cord
Structure Level Pattern Image Note
TS16: neural tube roof plate Present Diffuse 5I
TS16: neural tube floor plate Strong 5I
Specimen 5J: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord floor plate Strong 5J
TS20: spinal cord roof plate Strong 5J
TS20: spinal cord Present Regionally restricted 5J Expression is seen in horizontal stripes in the ventral spinal cord; it is notably absent in the dorsal ventricular zone.
TS20: dorsal root ganglion Absent 5J
Specimen 5L: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: limb interdigital region mesenchyme Present 5L
TS20: digit mesenchyme Absent 5L
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory