Gene Expression Data
Assay Details
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Assay
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Reference:
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J:275665
Wang LW, et al., Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage. Matrix Biol. 2019 Apr;77:117-128
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6479134
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Gene symbol:
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Fbn1
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Gene name:
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fibrillin 1
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Antibody:
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anti-rF6H
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Detection system:
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Secondary antibody coupled to Alexa Fluor 488
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Results
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Specimen
3C Adamts10+/+ 8 days:
postnatal day 8
(more  )
Specimen
3C Adamts10+/+ 8 days:
(close  )
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Genetic Background:
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Not Specified
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Age:
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postnatal day 8
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Sex:
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Not Specified
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Type:
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section
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Specimen
3C Adamts10-/- 8 days:
(close )
Specimen
3C Adamts10+/+ 6 weeks:
postnatal week 6
(more )
Specimen
3C Adamts10+/+ 6 weeks:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal week 6
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Sex:
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Not Specified
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Type:
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section
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Specimen
3C Adamts10-/- 6 weeks:
(close )
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: ciliary zonule |
Weak |
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3C Adamts10-/- 6 weeks
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Expression was reduced in the 6 week zonule of the mutant.
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Specimen
3C Adamts10+/+ 1 year:
postnatal year 1
(more )
Specimen
3C Adamts10+/+ 1 year:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal year 1
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Sex:
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Not Specified
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Type:
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section
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Specimen
3C Adamts10-/- 1 year:
(close )
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: ciliary zonule |
Present |
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3C Adamts10-/- 1 year
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At 1 year of age, expression in the mutant zonule was comparable to wild type.
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Analysis Tools