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Gene Expression Data
Assay Details
Assay
Reference: J:275665 Wang LW, et al., Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage. Matrix Biol. 2019 Apr;77:117-128
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6479048
Gene symbol: Adamts10
Gene name: ADAM metallopeptidase with thrombospondin type 1 motif 10
Reporter: lacZ
Direct Detection
Results
Specimen 1D: postnatal; Adamts10tm1Dgen/Adamts10+ (more )
Structure Level Pattern Image Note
TS28: aorta Present 1D Adamts10+/-
TS28: coronary artery Present 1D Adamts10+/-
TS28: left atrium Present 1D Adamts10+/-
TS28: right atrium Present 1D Adamts10+/-
TS28: ventricle cardiac muscle Absent 1D Adamts10+/-
Specimen not shown: embryonic day 12.5; Adamts10tm1Dgen/Adamts10+ (more )
Structure Level Pattern Image Note
TS20: eye Present
Specimen 2 E16.5 left: embryonic day 16.5; Adamts10tm1Dgen/Adamts10+ (more )
Structure Level Pattern Image Note
TS24: retina Present Regionally restricted 2_E16.5 left Expression was detected in the ciliary margin zone.
TS24: lens fiber Present Regionally restricted 2_E16.5 left Expression was detected in primary lens fibers.
TS24: retina layer Present Regionally restricted 2_E16.5 left Expression was detected in the ganglion cell layer.
Specimen 2 E16.5 right: embryonic day 16.5; Adamts10tm1Dgen/Adamts10+ (more )
Structure Level Pattern Image Note
TS24: retina Present Regionally restricted 2_E16.5 right Expression was detected in the ciliary margin zone.
TS24: lens fiber Present Regionally restricted 2_E16.5 right Expression was detected in primary lens fibers.
TS24: retina layer Present Regionally restricted 2_E16.5 right Expression was detected in the ganglion cell layer.
Specimen 2 Newborn left: postnatal newborn; Adamts10tm1Dgen/Adamts10+ (more )
Structure Level Pattern Image Note
TS27: ciliary body Present 2_Newborn left
TS27: lens fiber Present 2_Newborn left
TS27: retina ganglion cell layer Present 2_Newborn left
Specimen 2 Newborn right: postnatal newborn; Adamts10tm1Dgen/Adamts10+ (more )
Structure Level Pattern Image Note
TS27: retina ganglion cell layer Present 2_Neworn right
Specimen 2 P10 left: postnatal day 10; Adamts10tm1Dgen/Adamts10+ (more )
Structure Level Pattern Image Note
TS28: ciliary epithelium Present Regionally restricted 2_P10 left Expression was detected in the non-pigmented ciliary epithelium.
TS28: lens epithelium Present 2_P10 left
TS28: canal of Schlemm Present 2_P10 left
Specimen 2 P10 right: postnatal day 10; Adamts10tm1Dgen/Adamts10+ (more )
Structure Level Pattern Image Note
TS28: cornea stroma Present 2_P10 right
TS28: lens epithelium Present 2_P10 right
TS28: sclera Present Regionally restricted 2_P10 right Expression was detected in scleral stroma cells.
Specimen 2 Adult left: postnatal adult; Adamts10tm1Dgen/Adamts10+ (more )
Structure Level Pattern Image Note
TS28: ciliary epithelium Present Regionally restricted 2_Adult left Expression was detected in the non-pigmented ciliary epithelium.
TS28: canal of Schlemm Present 2_Adult left
TS28: lens epithelium Present 2_Adult left
Specimen 2 Adult right: postnatal adult; Adamts10tm1Dgen/Adamts10+ (more )
Structure Level Pattern Image Note
TS28: cornea endothelium Present 2_Adult right
TS28: cornea stroma Present 2_Adult right
TS28: lens epithelium Present 2_Adult right
TS28: sclera Present Regionally restricted 2_Adult right Expression was detected in scleral stroma cells.
Specimen S1A Paw: postnatal adult; Adamts10tm1Dgen/Adamts10+ (more )
Structure Level Pattern Image Note
TS28: forelimb tendon Strong S1A Paw
TS28: limb dermis Strong S1A Paw
Specimen S1A Skin: postnatal adult; Adamts10tm1Dgen/Adamts10+ (more )
Structure Level Pattern Image Note
TS28: limb dermis Present S1A Skin
Specimen S1A Liver: postnatal adult; Adamts10tm1Dgen/Adamts10+ (more )
Structure Level Pattern Image Note
TS28: liver vasculature Present Regionally restricted S1A Liver Expression was detected in major hepatic vessels.
TS28: liver parenchyma Absent S1A Liver Hepatic tissue showed no expression.
Specimen S1A Paw: embryonic day 17.5; Adamts10tm1Dgen/Adamts10+ (more )
Structure Level Pattern Image Note
TS25: carpal bone Present Regionally restricted S1A Paw section Section through carpal and metacarpal cartilage, showing expression by all chondrocytes.
TS25: metacarpal bone Present Regionally restricted S1A Paw section Section through carpal and metacarpal cartilage, showing expression by all chondrocytes.
TS25: interosseus muscle of hand Present S1A Paw section
Specimen S1A Skin: embryonic day 17.5; Adamts10tm1Dgen/Adamts10+ (more )
Structure Level Pattern Image Note
TS25: dermis Present S1A Skin section
TS25: epidermis Absent S1A Skin section
Specimen S1A Heart: embryonic day 17.5; Adamts10tm1Dgen/Adamts10+ (more )
Structure Level Pattern Image Note
TS25: aorta Strong S1A Heart section
TS25: pulmonary trunk Strong S1A Heart section
Specimen S1A Aortic root: embryonic day 17.5; Adamts10tm1Dgen/Adamts10+ (more )
Structure Level Pattern Image Note
TS25: aorta Present Regionally restricted S1A Aortic root section Expression was detected in the aortic wall of the aorta root.
TS25: aortic valve Present Regionally restricted S1A Aortic root section Expression was detected in the valve cusps.
Specimen S1A Lung: embryonic day 17.5; Adamts10tm1Dgen/Adamts10+ (more )
Structure Level Pattern Image Note
TS25: lung Present Widespread S1A Lung section
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory