Gene Expression Data
Assay Details
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Assay
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Reference:
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J:294964
Vincentz JW, et al., Variation in a Left Ventricle-Specific Hand1 Enhancer Impairs GATA Transcription Factor Binding and Disrupts Conduction System Development and Function. Circ Res. 2019 Aug 30;125(6):575-589
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6478020
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Gene symbol:
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Hcn4
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Gene name:
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hyperpolarization-activated, cyclic nucleotide-gated K+ 4
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Results
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Specimen
5H:
postnatal day 0
(more  )
Specimen
5H:
(close  )
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Genetic Background:
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involves: FVB
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Specimen
5I:
(close )
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Genetic Background:
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involves: FVB
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Mutant Allele(s):
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Rr132em1Abfi/Rr132em1Abfi
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: impulse conducting system |
Present |
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5I
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Expression is seen in the His bundle and left bundle branch; these are hyperplastic and abnormally dispersed.
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Analysis Tools
