About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:194894 Couesnon A, et al., CLIPR-59: a protein essential for neuromuscular junction stability during mouse late embryonic development. Development. 2013 Apr;140(7):1583-93
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6477284
Gene symbol: S100b
Gene name: S100 protein, beta polypeptide, neural
Antibody: anti-S-100
Results
Specimen 6Ba S-100: embryonic day 18.5; Clip3tm1.1Ics/Clip3+ (more )
Note: Triple labeled: red - S100b; green - alpha-Bungarotoxin; blue - Tubb3 (assay MGI:6477285).
Structure Level Pattern Image Note
TS26: diaphragm Present Regionally restricted 6Ba S-100 , 6Ba Merge Expression in Schwann cells capping neuromuscular junctions in both control and mutant diaphragm.
Specimen 6Bb S-100: embryonic day 18.5; Clip3tm1.1Ics/Clip3tm1.1Ics (more )
Note: Triple labeled: red - S100b; green - alpha-Bungarotoxin; blue - Tubb3 (assay MGI:6477285).
Structure Level Pattern Image Note
TS26: diaphragm Present Regionally restricted 6Bb S-100 , 6Bb Merge Expression in Schwann cells capping neuromuscular junctions in both control and mutant diaphragm.
Specimen 6Bc S-100: embryonic day 18.5; Clip3tm1.1Ics/Clip3+ (more )
Note: Triple labeled: red - S100b; green - alpha-Bungarotoxin; blue - Tubb3 (assay MGI:6477285).
Structure Level Pattern Image Note
TS26: diaphragm Present Regionally restricted 6Bc Merge , 6Bc S-100 Authors report normally shaped Schwann cells capping healthy neuromuscular junctions.
Specimen 6Bd S-100: embryonic day 18.5; Clip3tm1.1Ics/Clip3tm1.1Ics (more )
Note: Triple labeled: red - S100b; green - alpha-Bungarotoxin; blue - Tubb3 (assay MGI:6477285).
Structure Level Pattern Image Note
TS26: diaphragm Present Regionally restricted 6Bd Merge , 6Bd S-100 At tip of nerve branch, abnormally shaped Schwann cells observed next to shedding segments of disconnected axons.
Specimen S5Ba: embryonic day 18.5; Clip3tm1.1Ics/Clip3+ (more )
Note: Triple labeled: red - S100b; green - alpha-Bungarotoxin; blue - DAPI.
Structure Level Pattern Image Note
TS26: diaphragm Present Regionally restricted S5Ba Authors report similar Schwann cell extenstions in ventral part of diaphragm in both control and mutant.
Specimen S5Bb: embryonic day 18.5; Clip3tm1.1Ics/Clip3tm1.1Ics (more )
Note: Triple labeled: red - S100b; green - alpha-Bungarotoxin; blue - DAPI.
Structure Level Pattern Image Note
TS26: diaphragm Present Regionally restricted S5Bb Authors report similar Schwann cell extenstions in ventral part of diaphragm in both control and mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory