Gene Expression Data
Assay Details
Assay
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Reference:
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J:143548
Himes AD, et al., Premature differentiation and aberrant movement of pituitary cells lacking both Hes1 and Prop1. Dev Biol. 2009 Jan 1;325(1):151-61
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6471711
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Gene symbol:
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Pomc
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Gene name:
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pro-opiomelanocortin-alpha
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Antibody:
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anti-ACTH
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
2E:
embryonic day 14.5
(more )
Specimen
2E:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formaldehyde
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Embedding:
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Paraffin
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Specimen
2F:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Hes1tm1Fgu/Hes1tm1Fgu
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formaldehyde
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Embedding:
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Paraffin
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Specimen
2G:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Prop1df/Prop1df
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formaldehyde
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Embedding:
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Paraffin
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Specimen
2H:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Hes1tm1Fgu/Hes1tm1Fgu Prop1df/Prop1df
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS22: remnant of Rathke's pouch |
Present |
Widespread |
2H
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Expressing cells in ventral part of Rathke's pouch and additionally located ectopically in dorsocaudal and dorsorostral Rathke's pouch.
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Specimen
S1A:
embryonic day 13.5
(more )
Specimen
S1A:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formaldehyde
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Embedding:
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Paraffin
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Specimen
S1B:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Hes1tm1Fgu/Hes1tm1Fgu
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Age:
|
embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formaldehyde
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Embedding:
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Paraffin
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Specimen
S1C:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Prop1df/Prop1df
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formaldehyde
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Embedding:
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Paraffin
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Specimen
S1D:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Hes1tm1Fgu/Hes1tm1Fgu Prop1df/Prop1df
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formaldehyde
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Embedding:
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Paraffin
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Specimen
E12.5 Wildtype not shown:
embryonic day 12.5
(more )
Specimen
E12.5 Wildtype not shown:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS20: pituitary gland |
Present |
|
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Authors report no difference among wildtype, Hes1 mutant, Prop1 mutant or double mutant pituitary.
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Specimen
E12.5 Hes1 mutant not shown:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Hes1tm1Fgu/Hes1tm1Fgu
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Age:
|
embryonic day 12.5
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Sex:
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Not Specified
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Type:
|
section
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Fixation:
|
Formaldehyde
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Embedding:
|
Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: pituitary gland |
Present |
|
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Authors report no difference among wildtype, Hes1 mutant, Prop1 mutant or double mutant pituitary.
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Specimen
E12.5 Prop1 mutant not shown:
embryonic day 12.5; Prop1df/ Prop1df
(more )
Specimen
E12.5 Prop1 mutant not shown:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Prop1df/Prop1df
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formaldehyde
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Embedding:
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Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: pituitary gland |
Present |
|
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Authors report no difference among wildtype, Hes1 mutant, Prop1 mutant or double mutant pituitary.
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Specimen
E12.5 Double mutant not shown:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Hes1tm1Fgu/Hes1tm1Fgu Prop1df/Prop1df
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Age:
|
embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
Formaldehyde
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Embedding:
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Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: pituitary gland |
Present |
|
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Authors report no difference among wildtype, Hes1 mutant, Prop1 mutant or double mutant pituitary.
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Specimen
2I:
embryonic day 16.5
(more )
Specimen
2I:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formaldehyde
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Embedding:
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Paraffin
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Specimen
2J:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Hes1tm1Fgu/Hes1tm1Fgu
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
|
section
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Fixation:
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Formaldehyde
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Embedding:
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Paraffin
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Specimen
2K:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Prop1df/Prop1df
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Age:
|
embryonic day 16.5
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Sex:
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Not Specified
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Type:
|
section
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Fixation:
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Formaldehyde
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Embedding:
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Paraffin
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Specimen
2L:
(close )
Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Hes1tm1Fgu/Hes1tm1Fgu Prop1df/Prop1df
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Age:
|
embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
Formaldehyde
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Embedding:
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Paraffin
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