Dyrk1a RT-PCR Gene Expression Assay - GXD

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Gene Expression Data
Assay Details

Assay

Reference:	J:241781 McElyea SD, et al., Influence of prenatal EGCG treatment and Dyrk1a dosage reduction on craniofacial features associated with Down syndrome. Hum Mol Genet. 2016 Nov 15;25(22):4856-4869
Assay type:	RT-PCR
MGI Accession ID:	MGI:6469257
Gene symbol:	Dyrk1a
Gene name:	dual-specificity tyrosine phosphorylation regulated kinase 1a

Probe:	Dyrk1a-pI, Dyrk1a-pJ
Assay notes:	Real-time quatntitative RT-PCR. Relative expression is shown normalized to Ev1 expression.

Results

Image: 1B Dyrk1a

	Sample Information		Bands	Other Sample Information
Lane	Age	Structure	Size Not Specified	Amount	Genetic Background	Mutant Allele(s)	Sex	Note
PA1	E9.5	TS15: 1st branchial arch	Present (a)	Not Specified	B6EiC3Sn a/A-Ts(17¹⁶)65Dn/J	Ts(17¹⁶)65Dn/0	Not Specified	Embryo with 21-24 somites.
NT	E9.5	TS15: neural tube	Present (a)	Not Specified	B6EiC3Sn a/A-Ts(17¹⁶)65Dn/J	Ts(17¹⁶)65Dn/0	Not Specified	Embryo with 21-24 somites.

Notes:
(a) Expression was significantly upregulated in the trisomic embryos relative to euploid littermates.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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