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Gene Expression Data
Assay Details
Assay
Reference: J:180304 Tu X, et al., Indian hedgehog requires additional effectors besides Runx2 to induce osteoblast differentiation. Dev Biol. 2012 Feb 1;362(1):76-82
Assay type: RNA in situ
MGI Accession ID: MGI:6468255
Gene symbol: Sp7
Gene name: Sp7 transcription factor 7
Probe: Osx probe5
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 3D1: embryonic day 18.5; Gt(ROSA)26Sortm3(Runx2)Flng/Gt(ROSA)26Sor+ (more )
Structure Level Pattern Image Note
TS26: tibia Present Regionally restricted 3D1 Expression in perichondrium.
Specimen 3D2: embryonic day 18.5; Runx2tm1Mjo/Runx2tm1Mjo (more )
Structure Level Pattern Image Note
TS26: tibia Absent 3D2 No expression in perichondrium.
Specimen 3D3: embryonic day 18.5; Gt(ROSA)26Sortm3(Runx2)Flng/Gt(ROSA)26Sor+, Runx2tm1Mjo/Runx2tm1Mjo, Tg(Col2a1-cre)3Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: tibia Present 3D3 Authors report expression was induced.
Specimen 3D4: embryonic day 18.5; Gt(ROSA)26Sortm3(Runx2)Flng/Gt(ROSA)26Sortm3(Runx2)Flng, Runx2tm1Mjo/Runx2tm1Mjo, Tg(Col2a1-cre)3Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: tibia Present 3D4 Authors report expression was induced.
Specimen 6A5: embryonic day 18.5; Gt(ROSA)26Sortm2(Gli2*)Flng/Gt(ROSA)26Sor+, Tg(Col2a1-cre)3Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: tibia Present 6A5
Specimen 6B5: embryonic day 18.5; Ihhtm1Amc/Ihhtm1Amc (more )
Structure Level Pattern Image Note
TS26: fibula Absent 6B5
TS26: tibia Absent 6B5
Specimen 6C5: embryonic day 18.5; Gt(ROSA)26Sortm3(Runx2)Flng/Gt(ROSA)26Sor+, Ihhtm1Amc/Ihhtm1Amc, Tg(Col2a1-cre)3Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: fibula Absent 6C5 Expression not induced in perichondrium.
TS26: tibia Absent 6C5 Expression not induced in perichondrium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory