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Gene Expression Data
Assay Details
Assay
Reference: J:228856 DiTommaso T, et al., Keratin 76 is required for tight junction function and maintenance of the skin barrier. PLoS Genet. 2014 Oct;10(10):e1004706
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6456598
Gene symbol: Tjp1
Gene name: tight junction protein 1
Results
Specimen S2A +/+: postnatal adult (more )
Note: Triple labeled: red - ZO-1 (Tjp1); green - Krt76 (assay MGI:6456583); blue - DAPI
Structure Level Pattern Image Note
TS28: metapodial pad epidermis Present Regionally restricted S2A +/+ Co-expression with Krt76 in suprabasal cells of paw pad.

Specimen S2A tm1a/tm1a: postnatal adult; Krt76tm1a(KOMP)Wtsi/Krt76tm1a(KOMP)Wtsi (more )
Note: Triple labeled: red - ZO-1 (Tjp1); green - Krt76 (assay MGI:6456583); blue - DAPI
Structure Level Pattern Image Note
TS28: metapodial pad epidermis Present Regionally restricted S2A tm1a/tm1a No obvious changes in localization of expression.

Specimen S2B +/+: postnatal adult (more )
Note: Triple labeled: green - ZO-1 (Tjp1); red - Krt14 (assay MGI:6456584); blue - DAPI.
Structure Level Pattern Image Note
TS28: metapodial pad epidermis Present Regionally restricted S2B +/+

Specimen S2B tm1a/tm1a: postnatal adult; Krt76tm1a(KOMP)Wtsi/Krt76tm1a(KOMP)Wtsi (more )
Note: Triple labeled: green - ZO-1 (Tjp1); red - Krt14 (assay MGI:6456584); blue - DAPI.
Structure Level Pattern Image Note
TS28: metapodial pad epidermis Present Regionally restricted S2B tm1a/tm1a No obvious changes in localization of expression.

Specimen S2F +/+: postnatal adult (more )
Note: Triple labeled: red - ZO-1 (Tjp1); green - Krt76 (assay MGI:6456583); blue - DAPI
Structure Level Pattern Image Note
TS28: metapodial pad epidermis Present S2F +/+

Specimen S2F No wound: postnatal adult; Krt76tm1a(KOMP)Wtsi/Krt76tm1a(KOMP)Wtsi (more )
Note: Triple labeled: red - ZO-1 (Tjp1); green - Krt14 (assay MGI:6456584); blue - DAPI.
Structure Level Pattern Image Note
TS28: metapodial pad epidermis Present S2F No wound


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory