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Gene Expression Data
Assay Details
Assay
Reference: J:251190 Hammock EA, et al., Developmental expression mapping of a gene implicated in multiple neurodevelopmental disorders, A2bp1 (Fox1). Dev Neurosci. 2011;33(1):64-74
Assay type: RNA in situ
MGI Accession ID: MGI:6452638
Gene symbol: Rbfox1
Gene name: RNA binding protein, fox-1 homolog (C. elegans) 1
Probe: MGC clone 69598
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2 top row: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forebrain Weak Regionally restricted 2_upper 1 , 2_upper 5 , 2_right upper , 2_upper 6 , 2_upper 4 , 2_upper 2 , 2_upper 3 Expressed in a small number of cells in proliferative zones lining the ventricle. Expressed in pallidal and striatal differentiating zones.

Specimen 2 middle row 1-3: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forebrain Weak Regionally restricted 2_middle 3 , 2_middle 2 , 2_middle 1 Expressed in a small number of cells in proliferative zones lining the ventricle.

Specimen 2 middle row 4-6: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forebrain Weak Regionally restricted 2_middle 4 , 2_middle 5 , 2_right lower , 2_middle 6 Expressed in a small number of cells in proliferative zones lining the ventricle. Expressed in pallidal and striatal differentiating zones.
TS19: neural tube floor plate Very strong 2_middle 5 , 2_middle 4 , 2_middle 6

Specimen 2 bottom row 1-3: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: diencephalon Present Regionally restricted 2_lower 1 , 2_lower 2 , 2_lower 3 Expressed in the geniculate pretectum and hypothalamus.
TS19: future spinal cord Present Regionally restricted 2_lower 1 , 2_lower 2 , 2_lower 3 Expressed in ventral motor column.

Specimen 2 bottom row 4-6: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: future spinal cord Present Regionally restricted 2_lower 4 , 2_lower 6 , 2_lower 5 Expressed in ventral motor column.

Specimen 3 top row: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: corpus striatum Strong Regionally restricted 3_upper 1 , 3_upper 2 , 3_upper 5 , 3_upper 3 , 3_upper 4 Expressed in the differentiating zone.
TS20: telencephalon Present Regionally restricted 3_upper 5 Expressed in the septum.

Specimen 3 middle row 1-2: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: corpus striatum Strong Regionally restricted 3_middle 2 , 3_middle 1 Expressed in the differentiating zone.
TS20: hypothalamus Strong Regionally restricted 3_middle 2 Expressed in the anterobasal nucleus.
TS20: preoptic area Strong Regionally restricted 3_middle 2 Expressed in the preoptic differentiating zone.

Specimen 3 middle row 3-4: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: corpus striatum Strong Regionally restricted 3_middle 4 , 3_middle 3 Expressed in the differentiating zone.
TS20: hypothalamus Strong Regionally restricted 3_middle 3 Expressed in the arcuate nucleus.
TS20: telencephalon Strong Regionally restricted 3_middle 3 Expressed in the pallidum.

Specimen 3 middle row 5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hypothalamus Strong Regionally restricted 3_middle 5 Expressed in the lateral region.
TS20: pons Strong Regionally restricted 3_middle 5 Expressed in the vental pontine differentiating zone and the facial motor nucleus.
TS20: medulla oblongata Strong Regionally restricted 3_middle 5 Expressed in differentiating zone.

Specimen 3 bottom row: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: pons Strong Regionally restricted 3_lower 4 , 3_lower 1 , 3_lower 2 , 3_lower 3 Expressed in the pontine reticular formation.

Specimen 4 1st row 1-4: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cortical plate Strong 4_1st row 3 , 4_1st row 1 , 4_1st row 4 , 4_1st row 2

Specimen 4 1st row 5-6: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cortical plate Strong 4_1st row 6 , 4_1st row 5
TS21: telencephalon Strong Regionally restricted 4_1st row 5 , 4_1st row 6 Expressed in the lateral septum.
TS21: corpus striatum Strong Regionally restricted 4_1st row 6 , 4_1st row 5 Expressed in the differentiating zone.

Specimen 4 2nd row 1-2: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cortical plate Strong 4_2nd row 1 , 4_2nd row 2
TS21: corpus striatum Strong Regionally restricted 4_2nd row 2 , 4_2nd row 1 Expressed in the differentiating zone.
TS21: telencephalon Strong Regionally restricted 4_2nd row 2 , 4_2nd row 1 Expressed in the lateral septum.

Specimen 4 2nd row 3-6: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cortical plate Strong 4_2nd row 3 , 4_2nd row 4 , 4_2nd row 5 , 4_2nd row 6
TS21: hypothalamus Strong Regionally restricted 4_2nd row 6 , 4_2nd row 5 , 4_2nd row 4 , 4_2nd row 3 Expressed in anterior hypothalamus.
TS21: telencephalon Strong Regionally restricted 4_2nd row 5 , 4_2nd row 4 , 4_2nd row 3 , 4_2nd row 6 Expressed in the amygdala, the most lateral regions of the dorsal pallium and lateral migratory stream.
TS21: trigeminal nerve Strong 4_2nd row 5 , 4_2nd row 3 , 4_2nd row 4 , 4_2nd row 6

Specimen 4 3rd row 1-2: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cortical plate Strong 4_3rd row 2 , 4_3rd row 1
TS21: thalamus Strong Regionally restricted 4_3rd row 1 , 4_3rd row 2 Expressed in the dorsal region.

Specimen 4 3rd row 3-6: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cortical plate Strong 4_3rd row 3 , 4_3rd row 5 , 4_3rd row 6 , 4_3rd row 4
TS21: thalamus Strong Regionally restricted 4_3rd row 5 , 4_3rd row 3 , 4_3rd row 4 , 4_3rd row 6 Expressed in the dorsal region.
TS21: telencephalon Strong Regionally restricted 4_3rd row 4 , 4_3rd row 3 , 4_3rd row 6 , 4_3rd row 5 Expressed in the bed nucleus of the stria terminalis.

Specimen 4 4th row: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hypothalamus Strong 4_4th row 2 , 4_4th row 5 , 4_4th row 4 , 4_4th row 1 , 4_4th row 3 Expressed in the preoptic and ventromedial region.

Specimen 5 1st row: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cortical plate Strong Regionally restricted 5_1st row 5 , 5_1st row 4 , 5_1st row 6 , 5_1st row 1 , 5_1st row 3 , 5_1st row 2 Expressed in the dorsal pallium.

Specimen 5 2nd row: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cortical plate Strong Regionally restricted 5_2nd row 3 , 5_2nd row 4 , 5_2nd row 2 , 5_2nd row 1 , 5_2nd row 5 , 5_2nd row 6 Expressed in the dorsal pallium.
TS22: amygdala Strong 5_2nd row 1 , 5_2nd row 2 , 5_2nd row 6 , 5_2nd row 5 , 5_2nd row 4 , 5_2nd row 3
TS22: corpus striatum Strong 5_2nd row 1 , 5_2nd row 2 , 5_2nd row 6 , 5_2nd row 5 , 5_2nd row 4 , 5_2nd row 3
TS22: external capsule Strong 5_2nd row 1 , 5_2nd row 2 , 5_2nd row 6 , 5_2nd row 5 , 5_2nd row 4 , 5_2nd row 3
TS22: basal forebrain Strong Regionally restricted 5_2nd row 4 , 5_2nd row 6 , 5_2nd row 5 , 5_2nd row 1 , 5_2nd row 2 , 5_2nd row 3 Expressed in postmitotic cells in the lateral regions.

Specimen 5 3rd row: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: external capsule Strong 5_3rd row 2 , 5_3rd row 6 , 5_3rd row 5 , 5_3rd row 4 , 5_3rd row 3 , 5_3rd row 1
TS22: cortical plate Strong Regionally restricted 5_3rd row 1 , 5_3rd row 2 , 5_3rd row 5 , 5_3rd row 3 , 5_3rd row 4 , 5_3rd row 6 Expressed in the dorsal pallium.
TS22: facial nerve Strong 5_3rd row 6 , 5_3rd row 2 , 5_3rd row 4 , 5_3rd row 1 , 5_3rd row 5 , 5_3rd row 3
TS22: trigeminal nerve Strong 5_3rd row 6 , 5_3rd row 2 , 5_3rd row 4 , 5_3rd row 1 , 5_3rd row 5 , 5_3rd row 3

Specimen 5 4th row: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: facial nerve Strong 5_4th row 5 , 5_4th row 2 , 5_4th row 1 , 5_4th row 4 , 5_4th row 3
TS22: trigeminal nerve Strong 5_4th row 5 , 5_4th row 2 , 5_4th row 1 , 5_4th row 4 , 5_4th row 3
TS22: brainstem Strong Regionally restricted 5_4th row 5 , 5_4th row 4 , 5_4th row 3 Exoressed in pontine reticular nucleus.

Specimen 6 1st row: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: accessory olfactory bulb Strong 6_1st row 1 , 6_1st row 3 , 6_1st row 5 , 6_1st row 4 , 6_1st row 2
TS28: cerebral cortex Strong 6_1st row 1 , 6_1st row 3 , 6_1st row 5 , 6_1st row 4 , 6_1st row 2
TS28: olfactory tract Strong Regionally restricted 6_1st row 3 , 6_1st row 5 , 6_1st row 2 , 6_1st row 4 , 6_1st row 1 Expressed in the accessory olfactory tract.

Specimen 6 2nd row: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Strong 6_2nd row 3 , 6_2nd row 5 , 6_2nd row 1 , 6_2nd row 2 , 6_2nd row 4

Specimen 6 3rd row: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: accumbens nucleus Strong 6_3rd row 5 , 6_3rd row 4 , 6_3rd row 3 , 6_3rd row 1 , 6_3rd row 2
TS28: pallidum Absent 6_3rd row 5

Specimen 6 4th row: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Strong 6_4th row 3 , 6_4th row 1 , 6_4th row 5 , 6_4th row 4 , 6_4th row 2
TS28: corpus striatum Strong 6_4th row 3 , 6_4th row 1 , 6_4th row 5 , 6_4th row 4 , 6_4th row 2
TS28: globus pallidus Absent 6_4th row 5 , 6_4th row 4

Specimen 6 5th row: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: thalamus Strong Regionally restricted 6_5th row 5 , 6_5th row 3 , 6_5th row 2 , 6_5th row 4 , 6_5th row 1 Expressed in the mediodorsal thalamus.
TS28: habenula Absent 6_5th row 5
TS28: hippocampus Strong 6_5th row 4 , 6_5th row 5 , 6_5th row 3

Specimen 6 6th row: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: hippocampus Strong 6_6th row 5 , 6_6th row 2 , 6_6th row 4 , 6_6th row 3 , 6_6th row 1

Specimen 6 7th row: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: substantia nigra Absent 6_7th row 2 , 6_7th row 1 , 6_7th row 3 , 6_7th row 4 , 6_7th row 5
TS28: midbrain tegmentum Present Regionally restricted 6_7th row 1 , 6_7th row 2 , 6_7th row 4 , 6_7th row 5 , 6_7th row 3 No expression in the ventral tegmental area.
TS28: hippocampus Strong 6_7th row 1 , 6_7th row 2

Specimen 6 8th row: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: neocortex Strong 6_8th row 4 , 6_8th row 1 , 6_8th row 2 , 6_8th row 5 , 6_8th row 3

Specimen 7 top row 1: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: amygdala Present 7_1st row 1
TS26: hypothalamus Present Regionally restricted 7_1st row 1 Expressed in the anterior hypothalamus.

Specimen 7 top row 2: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: dentate gyrus Present 7_1st row 2
TS26: hippocampus CA1 Present 7_1st row 2
TS26: hippocampus CA3 Present 7_1st row 2

Specimen 7 top row 3: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cortical plate Present 7_1st row 3

Specimen 7 top row 4: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: globus pallidus Absent 7_1st row 4

Specimen 7 bottom row 1: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: amygdala Present 7_2nd row 1
TS28: hypothalamus Present Regionally restricted 7_2nd row 1 Expressed in the anterior hypothalamus.

Specimen 7 bottom row 2: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Present 7_2nd row 2
TS28: hippocampus CA1 Present 7_2nd row 2
TS28: hippocampus CA3 Present 7_2nd row 2

Specimen 7 bottom row 3: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: neocortex Present Regionally restricted 7_2nd row 3 Expressed in more mature laminated cortex.

Specimen 7 bottom row 4: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: globus pallidus Absent 7_2nd row 4

Specimen 8a: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lateral ganglionic eminence Absent 8a
TS20: medial ganglionic eminence Absent 8a
TS20: cerebral cortex Present 8a mantle

Specimen 8b: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Present Regionally restricted 8b Expressed in the mantle, the corticostriatal boundary, the lateral migratory stream and the cortical plate.
TS21: cortical plate Present 8b

Specimen 8c: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Present Regionally restricted 8c Expressed along the medial surface.

Specimen 8d: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex ventricular layer Absent 8d
TS23: cerebral cortex intermediate zone Present 8d
TS23: cerebral cortex marginal layer Present 8d
TS23: cerebral cortex subventricular zone Present 8d
TS23: cortical subplate Present 8d
TS23: cortical plate Present 8d Highest expression.

Specimen S1: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: diencephalon Present S1
TS23: hindbrain Present S1
TS23: midbrain Present S1
TS23: telencephalon Present S1

Specimen S2: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: diencephalon Present S2
TS24: hindbrain Present S2
TS24: midbrain Present S2
TS24: telencephalon Present S2

Specimen S3: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: diencephalon Present S3
TS25: hindbrain Present S3
TS25: midbrain Present S3
TS25: telencephalon Present S3

Specimen S4: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: diencephalon Present S4
TS26: hindbrain Present S4
TS26: midbrain Present S4
TS26: telencephalon Present S4


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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory