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Gene Expression Data
Assay Details
Assay
Reference: J:292476 Yin Y, et al., FGF9 and FGF10 activate distinct signaling pathways to direct lung epithelial specification and branching. Sci Signal. 2020 Mar 3;13(621)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6451704
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Results
Specimen 3A Sox2 Fgf9-/+: embryonic day 13.5; Fgf9tm1Dor/Fgf9+ (more )
Note: Double labeled: red - Sox2; green - Sox9 (assay MGI:6451705).
Structure Level Pattern Image Note
TS21: lung Present 3A Fgf9-/+ (merge) , 3A Fgf9-/+ SOX2
Specimen 3A Sox2 Fgf9-/-: embryonic day 13.5; Fgf9tm1Dor/Fgf9tm1Dor (more )
Note: Double labeled: red - Sox2; green - Sox9 (assay MGI:6451705).
Structure Level Pattern Image Note
TS21: lung Strong Regionally restricted 3A Fgf9-/- SOX2 , 3A Fgf9-/- (merge) Greatly expanded proximal domain compared to heterozygous controls.
Specimen S5A Sox2 Control: embryonic day 12.5 (more )
Note: Double labeled: red - Sox2; green - Sox9 (assay MGI:6451705).
Structure Level Pattern Image Note
TS20: lung Present S2A Control (merge) , S2A Control SOX2
Specimen S5A Sox2 Fgfr3-/-: embryonic day 12.5; Fgfr3tm1Dor/Fgfr3tm1Dor (more )
Note: Double labeled: red - Sox2; green - Sox9 (assay MGI:6451705).
Structure Level Pattern Image Note
TS20: lung Strong Regionally restricted S2A Fgfr3-/- (merge) , S2A Fgfr3-/- SOX2 Distal expansion of expression.
Specimen S5B Sox2 Control: embryonic day 12.5 (more )
Note: Double labeled: red - Sox2; green - Sox9 (assay MGI:6451705).
Structure Level Pattern Image Note
TS20: lung Present S2B Control (merge) , S2B Control SOX2
Specimen S5B Sox2 Fgfr3-/-: embryonic day 12.5; Fgfr3tm1Dor/Fgfr3tm1Dor (more )
Note: Double labeled: red - Sox2; green - Sox9 (assay MGI:6451705).
Structure Level Pattern Image Note
TS20: lung Strong Regionally restricted S2B Fgfr3-/- (merge) , S2B Fgfr3-/- SOX2 Increase in region of epithelium expressing both Sox2 and Sox9.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory