About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:292476 Yin Y, et al., FGF9 and FGF10 activate distinct signaling pathways to direct lung epithelial specification and branching. Sci Signal. 2020 Mar 3;13(621)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6451704
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Results
Specimen 3A Sox2 Fgf9-/+: embryonic day 13.5; Fgf9tm1Dor/Fgf9+ (more )
Note: Double labeled: red - Sox2; green - Sox9 (assay MGI:6451705).
Structure Level Pattern Image Note
TS21: lung Present 3A Fgf9-/+ (merge) , 3A Fgf9-/+ SOX2
Specimen 3A Sox2 Fgf9-/-: embryonic day 13.5; Fgf9tm1Dor/Fgf9tm1Dor (more )
Note: Double labeled: red - Sox2; green - Sox9 (assay MGI:6451705).
Structure Level Pattern Image Note
TS21: lung Strong Regionally restricted 3A Fgf9-/- SOX2 , 3A Fgf9-/- (merge) Greatly expanded proximal domain compared to heterozygous controls.
Specimen S5A Sox2 Control: embryonic day 12.5 (more )
Note: Double labeled: red - Sox2; green - Sox9 (assay MGI:6451705).
Structure Level Pattern Image Note
TS20: lung Present S2A Control (merge) , S2A Control SOX2
Specimen S5A Sox2 Fgfr3-/-: embryonic day 12.5; Fgfr3tm1Dor/Fgfr3tm1Dor (more )
Note: Double labeled: red - Sox2; green - Sox9 (assay MGI:6451705).
Structure Level Pattern Image Note
TS20: lung Strong Regionally restricted S2A Fgfr3-/- (merge) , S2A Fgfr3-/- SOX2 Distal expansion of expression.
Specimen S5B Sox2 Control: embryonic day 12.5 (more )
Note: Double labeled: red - Sox2; green - Sox9 (assay MGI:6451705).
Structure Level Pattern Image Note
TS20: lung Present S2B Control (merge) , S2B Control SOX2
Specimen S5B Sox2 Fgfr3-/-: embryonic day 12.5; Fgfr3tm1Dor/Fgfr3tm1Dor (more )
Note: Double labeled: red - Sox2; green - Sox9 (assay MGI:6451705).
Structure Level Pattern Image Note
TS20: lung Strong Regionally restricted S2B Fgfr3-/- (merge) , S2B Fgfr3-/- SOX2 Increase in region of epithelium expressing both Sox2 and Sox9.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory