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Gene Expression Data
Assay Details
Assay
Reference: J:292476 Yin Y, et al., FGF9 and FGF10 activate distinct signaling pathways to direct lung epithelial specification and branching. Sci Signal. 2020 Mar 3;13(621)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6451705
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Results
Specimen 3A Sox9 Fgf9-/+: embryonic day 13.5; Fgf9tm1Dor/Fgf9+ (more )
Note: Double labeled: green - Sox9; red - Sox2 (assay MGI:6451704).
Structure Level Pattern Image Note
TS21: lung Present 3A Fgf9-/+ (merge) , 3A Fgf9-/+ SOX9
Specimen 3A Sox9 Fgf9-/-: embryonic day 13.5; Fgf9tm1Dor/Fgf9tm1Dor (more )
Note: Double labeled: green - Sox9; red - Sox2 (assay MGI:6451704).
Structure Level Pattern Image Note
TS21: lung Weak Regionally restricted 3A Fgf9-/- SOX9 , 3A Fgf9-/- (merge) Expression restricted to most distal regions compared to heterozygous controls.
Specimen S5A Sox9 Control: embryonic day 12.5 (more )
Note: Double labeled: green - Sox9; red - Sox2 (assay MGI:6451704).
Structure Level Pattern Image Note
TS20: lung Present S2A Control SOX9 , S2A Control (merge)
Specimen S5A Sox9 Fgfr3-/-: embryonic day 12.5; Fgfr3tm1Dor/Fgfr3tm1Dor (more )
Note: Double labeled: green - Sox9; red - Sox2 (assay MGI:6451704).
Structure Level Pattern Image Note
TS20: lung Present S2A Fgfr3-/- SOX9 , S2A Fgfr3-/- (merge) Expression pattern similar to that of control.
Specimen S5B Sox9 Control: embryonic day 12.5 (more )
Note: Double labeled: green - Sox9; red - Sox2 (assay MGI:6451704).
Structure Level Pattern Image Note
TS20: lung Present S2B Control (merge) , S2B Control SOX9
Specimen S5B Sox9 Fgfr3-/-: embryonic day 12.5; Fgfr3tm1Dor/Fgfr3tm1Dor (more )
Note: Double labeled: green - Sox9; red - Sox2 (assay MGI:6451704).
Structure Level Pattern Image Note
TS20: lung Present Regionally restricted S2B Fgfr3-/- (merge) , S2B Fgfr3-/- SOX9 Increase in region of epithelium expressing both Sox2 and Sox9.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory