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Gene Expression Data
Assay Details
Assay
Reference: J:231259 Krill KT, et al., Dicer deficiency reveals microRNAs predicted to control gene expression in the developing adrenal cortex. Mol Endocrinol. 2013 May;27(5):754-68
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6451194
Gene symbol: Cdkn1a
Gene name: cyclin dependent kinase inhibitor 1A
Antibody: anti-p21
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 3A E14.5 Cre- WT: embryonic day 14.5; Dicer1tm1Bdh/? (more )
Note: Littermate controls could be flox/flox, or flox/+.
Structure Level Pattern Image Note
TS22: adrenal gland Present Regionally restricted 3A upper left Limited primarily to the cortex.
TS22: adrenal cortex Present 3A upper left

Specimen 3A E14.5 Cre+ KO: embryonic day 14.5; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(Nr5a1-cre)2Klp/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: adrenal cortex Present 3A lower left Increased expression compared with the control.

Specimen 3A E16.5 Cre- WT: embryonic day 16.5; Dicer1tm1Bdh/? (more )
Note: Littermate controls could be flox/flox, or flox/+.
Structure Level Pattern Image Note
TS24: adrenal cortex Present 3A upper middle

Specimen 3A E16.5 Cre+ KO: embryonic day 16.5; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(Nr5a1-cre)2Klp/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: adrenal cortex Present 3A lower middle Increased expression compared with the control.

Specimen 3A E18.5 Cre- WT: embryonic day 18.5; Dicer1tm1Bdh/? (more )
Note: Littermate controls could be flox/flox, or flox/+.
Structure Level Pattern Image Note
TS26: adrenal gland Present 3A upper right

Specimen 3A E18.5 Cre+ KO: embryonic day 18.5; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(Nr5a1-cre)2Klp/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: adrenal gland Present 3A lower right Increased expression compared with the control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory