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Gene Expression Data
Assay Details
Assay
Reference: J:189955 Star EN, et al., Regulation of retinal interneuron subtype identity by the Iroquois homeobox gene Irx6. Development. 2012 Dec;139(24):4644-55
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6450173
Gene symbol: Irx5
Gene name: Iroquois homeobox 5
Antibody: Anti-Irx5
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 2M: postnatal month 2-3; Irx6tm1Chow/Irx6+ (more )
Note: Double labeled: red - Irx5; green - Irx6 (assay MGI:6450171).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted 2N , 2M Irx5 labels type 2 and 3 bipolar cells. Irx5 co-labeled with Irx6:b-gal positive cells in a subset of bipolar cells. Not all Irx5-positive cells co-labeled with Irx6:beta-gal, and not all Irx6:beta-gal positive cells co-labeled with Irx5.
Specimen 4E: postnatal month 2-3; Irx6tm1Chow/Irx6tm1Chow (more )
Note: Double labeled: red - Irx5; green - Irx6 (assay MGI:6450171).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted 4E , 4F Similar to the Irx6<+/lacZ> retina, labeling exhibited overlapping and non-overlapping expression with Irx6:bgal in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory