Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:278913
Meyer G, et al., Cajal-Retzius neurons are required for the development of the human hippocampal fissure. J Anat. 2019 Sep;235(3):569-589
|
|
Assay type:
|
Immunohistochemistry
|
|
MGI Accession ID:
|
MGI:6441741
|
|
Gene symbol:
|
Trp73
|
|
Gene name:
|
transformation related protein 73
|
|
Antibody:
|
anti-p73alpha C-terminal
|
|
Detection system:
|
Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
|
|
|
Results
|
Specimen
7C:
embryonic day 15.0
(more  )
Specimen
7C:
(close  )
|
Genetic Background:
|
involves: 129 * C57BL/6
|
|
Age:
|
embryonic day 15.0
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Paraffin
|
Specimen
7D:
embryonic day 15.0
(more )
Specimen
7D:
(close )
|
Genetic Background:
|
involves: 129 * C57BL/6
|
|
Age:
|
embryonic day 15.0
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS23: hippocampus |
Present |
Regionally restricted |
7D
|
Expression in Cajal-Retzius neurons in dorsal hippocampus, appear directly continuous with expressing choroid plexus epithelial cells.
|
| TS23: lateral ventricle choroid plexus |
Present |
Regionally restricted |
7D
|
Expression in epithelial cells.
|
Specimen
7E:
embryonic day 15.0
(more )
Specimen
7E:
(close )
|
Genetic Background:
|
involves: 129 * C57BL/6
|
|
Age:
|
embryonic day 15.0
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS23: cortical hem |
Present |
Regionally restricted |
7E
|
Expression in ventral cortical hem where Cajal-Retzius neurons for ventral hippocampal fissure are generated.
|
Specimen
7E inset:
embryonic day 15.5
(more )
Specimen
7E inset:
(close )
|
Genetic Background:
|
involves: 129 * C57BL/6
|
|
Age:
|
embryonic day 15.5
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS23: cortical hem |
Present |
Regionally restricted |
7E inset
|
Expression in ventral cortical hem at E15.5, when outmigrating of expressing cells reaches its maximum.
|
Specimen
7F:
embryonic day 15.0
(more )
Specimen
7F:
(close )
|
Genetic Background:
|
involves: 129 * C57BL/6
|
|
Age:
|
embryonic day 15.0
|
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS23: telencephalon |
Present |
Regionally restricted |
7F
|
Expression in caudal hippocampal fissure.
|
Specimen
9C:
postnatal day 1
(more )
Specimen
9C:
(close )
|
Genetic Background:
|
involves: 129 * C57BL/6
|
|
Age:
|
postnatal day 1
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Paraffin
|
Specimen
9D:
(close )
|
Genetic Background:
|
involves: 129 * C57BL/6
|
|
Mutant Allele(s):
|
Trp73tm1Fmc/Trp73tm1Fmc
|
|
Age:
|
postnatal day 1
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS27: hippocampal fissure |
Weak |
Single cells |
9D
|
Expression in only a few Cajal-Retzius neurons in rudimentary superficial hippocampal fissure.
|
Specimen
10A:
(close )
|
Genetic Background:
|
involves: 129 * C57BL/6
|
|
Mutant Allele(s):
|
Trp73tm1(cre)Agof/Trp73tm1(cre)Agof
|
|
Age:
|
postnatal day 2
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS27: hippocampal fissure |
Weak |
Regionally restricted |
10A
|
Expression in less numerous Cajal-Retzius neurons, irregularly distributed along hippocampal fissure, which appears shortened.
|
Specimen
10B:
postnatal day 1
(more )
Specimen
10B:
(close )
|
Genetic Background:
|
involves: 129 * C57BL/6
|
|
Age:
|
postnatal day 1
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Paraffin
|
Specimen
10C:
postnatal day 1
(more )
Specimen
10C:
(close )
|
Genetic Background:
|
involves: 129 * C57BL/6
|
|
Age:
|
postnatal day 1
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Paraffin
|
Specimen
10D:
(close )
|
Genetic Background:
|
involves: 129 * C57BL/6
|
|
Mutant Allele(s):
|
Trp73tm1Mak/Trp73tm1Mak
|
|
Age:
|
postnatal day 2
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS27: hippocampal fissure |
Present |
Regionally restricted |
10D
|
Expression in a number of Cajal-Retzius neurons in ventral hippocampal fissure.
|
| TS27: hippocampus |
Present |
Regionally restricted |
10D
|
Cajal-Retzius neurons almost absent in dorsal hippocampus.
|
| TS27: cerebral cortex marginal zone |
Absent |
|
10D
|
Cajal-Retzius neurons absent from medial cortical wall.
|
Specimen
10E:
(close )
|
Genetic Background:
|
involves: 129 * C57BL/6
|
|
Mutant Allele(s):
|
Trp73tm1(cre)Agof/Trp73tm1(cre)Agof
|
|
Age:
|
postnatal day 2
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Embedding:
|
Paraffin
|
|
Analysis Tools