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Gene Expression Data
Assay Details
Assay
Reference: J:278913 Meyer G, et al., Cajal-Retzius neurons are required for the development of the human hippocampal fissure. J Anat. 2019 Sep;235(3):569-589
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6441739
Gene symbol: Reln
Gene name: reelin
Results
Specimen 7B: embryonic day 15.0; Trp73tm1Fmc/Trp73tm1Fmc (more )
Note: Double labeled: green - Reln; red - Tbr1 (assay MGI:6441738).
Structure Level Pattern Image Note
TS23: cortical hem Present Regionally restricted 7B Co-expression with Tbr1 in Cajal-Retzius neurons originating in the cortical hem, which do not migrate dorsally and do not assemble in the aborted hippocampal fissure.
Specimen 7G: embryonic day 14.0 (more )
Note: Double labeled: green - Reln; red - Tbr1 (assay MGI:6441738).
Structure Level Pattern Image Note
TS22: cerebral cortex marginal layer Present Regionally restricted 7G Expression in Cajal-Retzius neurons.
Specimen 7H: embryonic day 14.0; Trp73tm1Mak/Trp73tm1Mak (more )
Note: Double labeled: green - Reln; red - Tbr1 (assay MGI:6441738).
Structure Level Pattern Image Note
TS22: cerebral cortex marginal layer Weak Regionally restricted 7H Authors report severely reduced Cajal-Retzius neuron density.
Specimen 7I: embryonic day 14.0; Trp73tm1(cre)Agof/Trp73tm1(cre)Agof (more )
Note: Double labeled: green - Reln; red - Tbr1 (assay MGI:6441738).
Structure Level Pattern Image Note
TS22: cerebral cortex marginal layer Present Regionally restricted 7I Cajal-Retzius neurons are slighly less numerous. General upregulation of expression compared with wild type.
Specimen 7J: embryonic day 14.0; Trp73tm1Fmc/Trp73tm1Fmc (more )
Note: Double labeled: green - Reln; red - Tbr1 (assay MGI:6441738).
Structure Level Pattern Image Note
TS22: cerebral cortex marginal layer Absent 7J Authors report complete absence of Cajal-Retzius neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory