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Gene Expression Data
Assay Details
Assay
Reference: J:289404 Rutledge EA, et al., Mutational analysis of genes with ureteric progenitor cell-specific expression in branching morphogenesis of the mouse kidney. Dev Dyn. 2020 Jun;249(6):765-774
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6441524
Gene symbol: Six2
Gene name: sine oculis-related homeobox 2
Antibody: anti-Six2 (11562-1-AP)
Detection system: Secondary antibody
Results
Specimen 4E: embryonic day 12.5 (more )
Note: This specimen was also stained with a cytokeratin antibody to mark the epithelium.
Structure Level Pattern Image Note
TS20: nephron Present 4E

Specimen 4F: embryonic day 12.5; D17H6S56E-5em1Amc/D17H6S56E-5+ (more )
Note: This specimen was also stained with a cytokeratin antibody to mark the epithelium.
Structure Level Pattern Image Note
TS20: nephron Present 4F

Specimen 4G: embryonic day 12.5; D17H6S56E-5em1Amc/D17H6S56E-5em1Amc (more )
Note: This specimen was also stained with a cytokeratin antibody to mark the epithelium.
Structure Level Pattern Image Note
TS20: nephron Present 4G Kidneys in the mutant appear normal, although 1 (of 28) displayed a double ureter. This frequency is not statistically different from spontaneous double ureter formation in the C57BL/6J mouse strain.

Specimen 4L: embryonic day 12.5 (more )
Note: This specimen was also stained with a cytokeratin antibody to mark the epithelium.
Structure Level Pattern Image Note
TS20: nephron Present 4L

Specimen 4M: embryonic day 12.5; Tmem59lem1Amc/Tmem59l+ (more )
Note: This specimen was also stained with a cytokeratin antibody to mark the epithelium.
Structure Level Pattern Image Note
TS20: nephron Present 4M

Specimen 4N: embryonic day 12.5; Tmem59lem1Amc/Tmem59lem1Amc (more )
Note: This specimen was also stained with a cytokeratin antibody to mark the epithelium.
Structure Level Pattern Image Note
TS20: nephron Present 4N Kidneys in the mutant appear normal, although 2 (of 23) displayed a double ureter. This is a statistically significant increase over the rate of spontaneous double ureter formation in the C57BL/6J mouse strain.

Specimen 4P: embryonic day 12.5; Hs3st3a1tm1(KOMP)Vlcg/Hs3st3a1+, Hs3st3b1em1Amc/Hs3st3b1+ (more )
Note: This specimen was also stained with a cytokeratin antibody to mark the epithelium.
Structure Level Pattern Image Note
TS20: nephron Present 4P

Specimen 4R: embryonic day 12.5; Hs3st3a1tm1(KOMP)Vlcg/Hs3st3a1tm1(KOMP)Vlcg, Hs3st3b1em1Amc/Hs3st3b1em1Amc (more )
Note: This specimen was also stained with a cytokeratin antibody to mark the epithelium.
Structure Level Pattern Image Note
TS20: nephron Present 4R Kidneys in the mutant appear normal, although 3 (of 28) displayed a double ureter. This is a statistically significant increase over the rate of spontaneous double ureter formation in the C57BL/6J mouse strain.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory