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Tmem59lem1Amc
Endonuclease-mediated Allele Detail
Summary
Symbol: Tmem59lem1Amc
Name: transmembrane protein 59-like; endonuclease-mediated mutation 1, Andrew P McMahon
MGI ID: MGI:6441470
Gene: Tmem59l  Location: Chr8:70936517-70940008 bp, - strand  Genetic Position: Chr8, 34.15 cM
Alliance: Tmem59lem1Amc page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsCRISPR-targeting deleted 804 bp spanning intron 1 through exon 3 results in a frame shift and premature termination. (J:289404)
Expression
In Mice Carrying this Mutation: 4 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tmem59l Mutation:  38 strains or lines available
References
Original:  J:289404 Rutledge EA, et al., Mutational analysis of genes with ureteric progenitor cell-specific expression in branching morphogenesis of the mouse kidney. Dev Dyn. 2020 Jun;249(6):765-774
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory