About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:229352 Metzger DE, et al., Grg3/TLE3 and Grg1/TLE1 induce monohormonal pancreatic beta-cells while repressing alpha-cell functions. Diabetes. 2014 May;63(5):1804-16
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6441185
Gene symbol: Tle1
Gene name: transducin-like enhancer of split 1
Antibody: anti-Grg1
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen S1A: embryonic day 17.5 (more )
Note: Double labeled: green - Tle1; red - Ins1 (assay MGI:6441181) and Ins2 (assay MGI:6441475).
Structure Level Pattern Image Note
TS25: islets of Langerhans Present Regionally restricted S1A right Tle1 did not stain the insulin+ cells.

Specimen S1B: postnatal newborn (more )
Note: Double labeled: green - Tle1; red - Ins1 (assay MGI:6441181) and Ins2 (assay MGI:6441475).
Structure Level Pattern Image Note
TS27: islets of Langerhans Ambiguous S1B right Tle1 did not stain the insulin+ cells.

Specimen S1C: postnatal adult (more )
Note: Double labeled: green - Tle1; red - Ins1 (assay MGI:6441181) and Ins2 (assay MGI:6441475).
Structure Level Pattern Image Note
TS28: islets of Langerhans Strong S1C right


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory