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Gene Expression Data
Assay Details
Assay
Reference: J:287484 Tomita H, et al., The Protein Tyrosine Phosphatase Receptor Delta Regulates Developmental Neurogenesis. Cell Rep. 2020 Jan 7;30(1):215-228.e5
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6437931
Gene symbol: Satb2
Gene name: special AT-rich sequence binding protein 2
Antibody: anti-SATB2 (SATBA4B10; ab51502)
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 5D WT: embryonic day 18.5 (more )
Note: Quantified in Fig 5E/F.
Structure Level Pattern Image Note
TS26: cerebral cortex Present 5D upper Expressed in the superficial layer cortical neurons.
Specimen 5D KO: embryonic day 18.5; Ptprdtm1Yiw/Ptprdtm1Yiw (more )
Note: Quantified in Fig 5E/F.
Structure Level Pattern Image Note
TS26: cerebral cortex Present 5D lower Significantly increased numbers of the positive neurons.
TS26: cerebral cortex intermediate zone Present 5D lower A higher relative proportion of total positive neurons relative to the wild-type.
TS26: cerebral cortex subventricular zone Present 5D lower A higher relative proportion of total positive neurons relative to the wild-type.
TS26: cerebral cortex ventricular zone Present 5D lower A higher relative proportion of total positive neurons relative to the wild-type.
TS26: cortical plate Present 5D lower A lower proportion of total positive neurons relative to the wild-type.
Specimen not shown: embryonic day 18.5; Ptprdtm1Yiw/Ptprd+ (more )
Note: Quantified in Fig 5E/F.
Structure Level Pattern Image Note
TS26: cerebral cortex Present Significantly increased numbers of the positive neurons.
TS26: cortical plate Present A lower proportion of total positive neurons relative to the wild-type.
TS26: cerebral cortex intermediate zone Present A higher relative proportion of total positive neurons relative to the wild-type.
TS26: cerebral cortex subventricular zone Present A higher relative proportion of total positive neurons relative to the wild-type.
TS26: cerebral cortex ventricular zone Present A higher relative proportion of total positive neurons relative to the wild-type.
Specimen 5J WT: postnatal day 7 (more )
Note: Quantified in Fig 5K/L.
Structure Level Pattern Image Note
TS28: cerebral cortex Present 5J left Expressed in the superficial layer cortical neurons.
Specimen 5J KO: postnatal day 7; Ptprdtm1Yiw/Ptprdtm1Yiw (more )
Note: Quantified in Fig 5K/L.
Structure Level Pattern Image Note
TS28: cerebral cortex Present 5J right Significantly increased numbers of the positive neurons.
Specimen not shown: postnatal day 7; Ptprdtm1Yiw/Ptprd+ (more )
Note: Quantified in Fig 5K/L.
Structure Level Pattern Image Note
TS28: cerebral cortex Present Similar as in the wild-type.
Specimen S3A: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex Present S3A Expressed in the superficial layer cortical neurons.
Specimen S3B: embryonic day 18.5 (more )
Note: Double labeled: red - Satb2; magenta - Tbr1 (assay MGI:6437933).
Structure Level Pattern Image Note
TS26: cerebral cortex Present S3B merge , S3B middle Expressed in the superficial layer cortical neurons.
Specimen S3C: postnatal day 7 (more )
Note: Double labeled: red - Satb2; green - Tbr1 (assay MGI:6437932).
Structure Level Pattern Image Note
TS28: cerebral cortex Present S3C middle , S3C merge Expressed in the superficial layer cortical neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory