Vcan Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:287334 Wunnemann F, et al., Loss of ADAMTS19 causes progressive non-syndromic heart valve disease. Nat Genet. 2020 Jan;52(1):40-47
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6437238
Gene symbol:	Vcan
Gene name:	versican

Antibody:	anti-cleaved versican (PA1-1748A)
Detection system:	Secondary antibody coupled to Alexa Fluor
Assay notes:	The antibody used in this assay recognizes the cleaved form of the protein.

Results

Specimen S5G: postnatal month 9 (more

)

Structure	Level	Pattern	Image	Note
TS28: aortic valve	Present		S5G

Specimen S5H: postnatal month 9; Adamts19^{tm4b(EUCOMM)Wtsi}/Adamts19^{tm4b(EUCOMM)Wtsi} (more

)
Note: The authors used two alleles interchangeably for these studies; it is possible the tm4a allele (MGI:5527601) was used to obtain these results.

Structure	Level	Pattern	Image	Note
TS28: aortic valve	Present		S5H

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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