Tg(S1pr2-cre/ERT2)#Kuro
Transgene Detail
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| Symbol: |
Tg(S1pr2-cre/ERT2)#Kuro |
| Name: |
transgene insertion, Tomohiro Kurosaki |
| MGI ID: |
MGI:6435090 |
| Synonyms: |
S1pr2-ERT2cre |
| Transgene: |
Tg(S1pr2-cre/ERT2)#Kuro Location: unknown
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| Alliance: |
Tg(S1pr2-cre/ERT2)#Kuro page
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| Transgene Type: |
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Transgenic (Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Tg(S1pr2-cre/ERT2)#Kuro expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
S1pr2 (MGI:99569) |
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Mutation details: An ERT2cre-encoding gene fused with a poly(A) signal and a neomycin-kanamycin resistance gene flanked with two FRT sites were inserted into the exon 2 of the S1pr2 gene, which encodes S1P2, on a BAC clone (RPCI23.C-168D6). Correctly targeted clones were injected into pronuclei of C57BL/6 zygotes to generate transgenic funder lines. The founder mice were identified by PCR and were further crossed with CAG-Flp transgenic mice to remove the neomycin-kanamycin resistance gene cassette. Line numbers were not indicated. The pound symbol (#) is used when no line is specified and/or lines are pooled.
(J:260241)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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S1pr2
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:260241 Shinnakasu R, et al., Regulated selection of germinal-center cells into the memory B cell compartment. Nat Immunol. 2016 Jul;17(7):861-9 |
| All: |
12 reference(s) |
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Analysis Tools
