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Gene Expression Data
Assay Details
Assay
Reference: J:138379 Gu S, et al., Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice. Mech Dev. 2008 Aug;125(8):729-42
Assay type: RNA in situ
MGI Accession ID: MGI:6434476
Gene symbol: Col2a1
Gene name: collagen, type II, alpha 1
Probe: Col II probe2
Probe preparation: labelled with digoxigenin RNA
Results
Specimen 8A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: mandible condylar condensation Trace 8A Expression initially detected in condylar condensation at E14.5.
TS22: Meckel's cartilage Present 8A
Specimen 8B: embryonic day 14.5; Shox2tm1Ddu/Shox2tm1Ypc, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: mandible condylar condensation Absent 8B
TS22: Meckel's cartilage Present 8B
Specimen 8C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: mandible condylar process Strong Regionally restricted 8C Strong expression in both immature and hypertrophic chondrocytes at E15.5
TS23: Meckel's cartilage Present 8C
Specimen 8D: embryonic day 15.5; Shox2tm1Ddu/Shox2tm1Ypc, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: mandible condylar process Weak 8D Expresssion detectable in mutant at E16.5.
TS23: Meckel's cartilage Present 8D
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory