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Gene Expression Data
Assay Details
Assay
Reference: J:138379 Gu S, et al., Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice. Mech Dev. 2008 Aug;125(8):729-42
Assay type: RNA in situ
MGI Accession ID: MGI:6434469
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Probe: Sox9 probe50
Probe preparation: labelled with digoxigenin RNA
Results
Specimen 6A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: mandible condylar condensation Present 6A
TS21: Meckel's cartilage Present 6A
Specimen 6B: embryonic day 13.5; Shox2tm1Ddu/Shox2tm1Ypc, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: mandible condylar condensation Weak 6B Significantly down-regulated expression in condylar condensation.
Specimen 7A: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: mandible condylar process Strong Regionally restricted 7A Strong expression in chondrocytes of wild type condyle.
TS23: mandibular fossa Absent 7A
Specimen 7B: embryonic day 15.5; Shox2tm1Ddu/Shox2tm1Ypc, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: mandible condylar process Weak Regionally restricted 7B Relatively reduced level of expression in chondryocytes of condyle.
TS23: mandibular fossa Absent 7B No expression in glenoid fossa.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory