Gene Expression Data
Assay Details
Assay
|
Reference:
|
J:235526
Jauregui EJ, et al., Parallel mechanisms suppress cochlear bone remodeling to protect hearing. Bone. 2016 Aug;89:7-15
|
Assay type:
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Immunohistochemistry
|
MGI Accession ID:
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MGI:6431010
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Gene symbol:
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Mmp13
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Gene name:
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matrix metallopeptidase 13
|
Antibody:
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anti-MMP-13 (AB8120)
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Detection system:
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Secondary antibody coupled to horseradish peroxidase
|
|
Results
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Specimen
1A E15:
embryonic day 15.0
(more )
Specimen
1A E15:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 15.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: cochlea |
Absent |
|
1B E15
,
1A E15
|
|
Specimen
1A E19:
embryonic day 19.0
(more )
Specimen
1A E19:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
embryonic day 19.0
|
Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: cochlea |
Absent |
|
1B E19
,
1A E19
|
|
Specimen
1A P1:
postnatal day 1
(more )
Specimen
1A P1:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
postnatal day 1
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: cochlea |
Absent |
|
1A P1
,
1B P1
|
|
Specimen
1A P5:
postnatal day 5
(more )
Specimen
1A P5:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
postnatal day 5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: cochlea |
Present |
|
1B P5
,
1A P5
|
|
Specimen
1A P10:
postnatal day 10
(more )
Specimen
1A P10:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
postnatal day 10
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: cochlea |
Present |
|
1A P10
,
1B P10
|
Expression declined from P5.
|
Specimen
1A P21:
postnatal day 21
(more )
Specimen
1A P21:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
postnatal day 21
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: cochlea |
Present |
|
1B P21
,
1A P21
|
|
Specimen
1A P60:
postnatal day 60
(more )
Specimen
1A P60:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
postnatal day 60
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: cochlea |
Present |
|
1B P60
,
1A P60
|
Expression increased compared to P21. Maximal levels were observed at P60 in the perilacunar regions surrounding osteocytes in the mid-cortical layer of the cochlear bone.
|
Specimen
S3A:
postnatal
(more )
Specimen
S3A:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
postnatal
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
S3B:
postnatal
(more )
Specimen
S3B:
(close )
Genetic Background:
|
FVB/N
|
Age:
|
postnatal
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
S3C:
(close )
Genetic Background:
|
involves: 129S2/SvPas * FVB/N
|
Mutant Allele(s):
|
Mmp13tm1.1Werb/Mmp13tm1.1Werb
|
Age:
|
postnatal
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
S3D:
(close )
Genetic Background:
|
involves: 129S2/SvPas * FVB/N
|
Mutant Allele(s):
|
Mmp13tm1.1Werb/Mmp13tm1.1Werb
|
Age:
|
postnatal
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
|