About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:192194 Tortelote GG, et al., Wnt3 function in the epiblast is required for the maintenance but not the initiation of gastrulation in mice. Dev Biol. 2013 Feb 1;374(1):164-73
Assay type: RNA in situ
MGI Accession ID: MGI:6430584
Gene symbol: Wnt3
Gene name: wingless-type MMTV integration site family, member 3
Probe: Wnt3 probe2
Probe preparation: labelled with digoxigenin RNA
Results
Specimen 1C: embryonic day 6.5; Wnt3tm2Amc/Wnt3+, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: embryo ectoderm Present 1C Authors report expression in the epiblast.
TS9: posterior visceral endoderm Present 1C
Specimen 1C Epi KO: embryonic day 6.5; Wnt3tm1Bhr/Wnt3tm2Amc, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: embryo ectoderm Absent 1C Epi KO Total absence of expression in epiblast.
TS9: posterior visceral endoderm Absent 1C Epi KO Expression also absent in posterior visceral endoderm.
Specimen 3A: embryonic day 6.0; Wnt3tm2Amc/Wnt3+, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS8: epiblast Present 3A
TS8: posterior visceral endoderm Present 3A
Specimen 3A Epi KO: embryonic day 6.0; Wnt3tm1Bhr/Wnt3tm2Amc, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS8: posterior visceral endoderm Present 3A Epi KO
Specimen 3B: embryonic day 6.0; Wnt3tm1Bhr/Wnt3tm2Amc, Edil3Tg(Sox2-cre)1Amc/Edil3+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS8: posterior visceral endoderm Present 3B Expression restricted to posterior visceral endoderm.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory