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Gene Expression Data
Assay Details
Assay
Reference: J:255612 Uysal F, et al., DNMT1, DNMT3A and DNMT3B proteins are differently expressed in mouse oocytes and early embryos. J Mol Histol. 2017 Dec;48(5-6):417-426
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6415120
Gene symbol: Dnmt3b
Gene name: DNA methyltransferase 3B
Antibody: anti-Dnmt3b (ab2851)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Assay notes: Relative expression levels are presented in Figs 3B and 4; expression levels gradually decreased and progressively increased during the time examined.
Results
Specimen 3A GV: postnatal (more )
Structure Level Pattern Image Note
TS28: primary oocyte Present 3A GV germinal vesicle-stage oocyte; expression is high in the nuclear region
Specimen 3A MII: postnatal (more )
Structure Level Pattern Image Note
TS28: secondary oocyte Present 3A MII metaphase II-stage oocyte
Specimen 3A 1C: embryonic day 0.5 (more )
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present 3A 1C expression is high in the nuclear region
Specimen 3A 2C: embryonic day 1.0 (more )
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Present 3A 2C expression is high in the nuclear region
Specimen 3A 4C: embryonic day 2.0 (more )
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Present 3A 4C
Specimen 3A 8C: embryonic day 2.5 (more )
Structure Level Pattern Image Note
TS3: 8-cell stage embryo Present 3A 8C
Specimen 3A M: embryonic day 3.0 (more )
Structure Level Pattern Image Note
TS3: compacted morula Present 3A M expression is high in the nuclear region
Specimen 3A B: embryonic day 3.5 (more )
Structure Level Pattern Image Note
TS4: blastocyst Present 3A B expression is stronger in the cytoplasm than the nucleus
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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