About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:203431 Collette NM, et al., Sost and its paralog Sostdc1 coordinate digit number in a Gli3-dependent manner. Dev Biol. 2013 Nov 1;383(1):90-105
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6406367
Gene symbol: Ctnnb1
Gene name: catenin beta 1
Antibody: Anti-Active-beta-Catenin (Anti-ABC) clone 8E7 (05-665)
Detection system: Alexa Fluor
Results
Specimen 9A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: limb epithelium Present 9A
TS20: limb mesenchyme Present 9A

Specimen 9B: embryonic day 12.5; Sosttm1Paz/Sosttm1Paz (more )
Structure Level Pattern Image Note
TS20: limb epithelium Strong 9B Expression up-regulated in ectoderm and underlying mesenchyme.
TS20: limb mesenchyme Strong 9B Expression up-regulated in ectoderm and underlying mesenchyme.

Specimen 9C: embryonic day 12.5; Gli3Xt-J/Gli3+ (more )
Structure Level Pattern Image Note
TS20: limb epithelium Present 9C Authors report lack of Sostdc1 has little effect on ectodermal experssion.
TS20: limb mesenchyme Weak 9C Slight reduction in mesenchymal expression.

Specimen 9D: embryonic day 12.5; Sosttm1Paz/Sosttm1Paz, Sostdc1tm1Myan/Sostdc1tm1Myan (more )
Structure Level Pattern Image Note
TS20: limb epithelium Trace 9D Dramatic reduction in both ectodermal and mesenchymal expression compared with wild type.
TS20: limb mesenchyme Trace 9D Dramatic reduction in both ectodermal and mesenchymal expression compared with wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory