Rac1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:282589 Rolo A, et al., Novel mouse model of encephalocele: post-neurulation origin and relationship to open neural tube defects. Dis Model Mech. 2019 Nov 14;12(11):dmm040683
Assay type:	RNA in situ
MGI Accession ID:	MGI:6404427
Gene symbol:	Rac1
Gene name:	Rac family small GTPase 1

Probe:	Rac1 cDNA2
Probe preparation:	Antisense labelled with digoxigenin RNA

Results

6A ©

6B ©

Specimen 6A: embryonic day 12.5; Grhl3^tm1(cre)Cgh/Grhl3⁺, Rac1^tm1Djk/Rac1⁺ (more

)
Note: Conditional mutant. The control was either Grhl3^Cre/+;Rac1^fl/+ or Grhl3^Cre/+;Rac1^-/+.

Structure	Level	Pattern	Image	Note
TS20: midbrain	Present		6A , 6B
TS20: skin	Present		6A , 6B	Expression was detected in the surface ectoderm.

6C ©

6D ©

Specimen 6C: embryonic day 12.5; Grhl3^tm1(cre)Cgh/Grhl3⁺, Rac1^tm1Djk/Rac1^tm1Djk (more

)
Note: Conditional mutant. The conditional knockout was either Grhl3^Cre/+;Rac1^fl/fl or Grhl3^Cre/+;Rac1^-/fl.

Structure	Level	Pattern	Image	Note
TS20: midbrain	Present		6D , 6C
TS20: skin	Absent		6C , 6D	Expression was specifically abolished in the mutant surface ectoderm.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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