Gene Expression Data
Assay Details
Assay
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Reference:
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J:223298
Park AC, et al., Homozygosity and Heterozygosity for Null Col5a2 Alleles Produce Embryonic Lethality and a Novel Classic Ehlers-Danlos Syndrome-Related Phenotype. Am J Pathol. 2015 Jul;185(7):2000-11
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6404121
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Gene symbol:
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Col5a2
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Gene name:
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collagen, type V, alpha 2
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Antibody:
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anti-alpha2(V)
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Detection system:
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Secondary antibody coupled to horseradish peroxidase
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Results
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Specimen
3C +/+:
embryonic day 11.5
(more )
Specimen
3C +/+:
(close )
Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6 * DBA/2
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS19: embryo mesenchyme |
Present |
Regionally restricted |
3C left
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Expressed juxtaposed to the basement membrane of the neuroepithelium.
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TS19: extracellular matrix |
Present |
Regionally restricted |
3C left
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Expressed juxtaposed to the basement membrane of the neuroepithelium.
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Specimen
3C +/-:
(close )
Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6 * DBA/2
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Mutant Allele(s):
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Col5a2tm1.2Dgr/Col5a2+
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS19: embryo mesenchyme |
Present |
Regionally restricted |
3C middle
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Diminished expression juxtaposed to the basement membrane of the neuroepithelium.
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TS19: extracellular matrix |
Present |
Regionally restricted |
3C middle
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Diminished expression juxtaposed to the basement membrane of the neuroepithelium.
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Specimen
3C -/-:
(close )
Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6 * DBA/2
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Mutant Allele(s):
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Col5a2tm1.2Dgr/Col5a2tm1.2Dgr
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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