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Gene Expression Data
Assay Details
Assay
Reference: J:280426 Matoba S, et al., Paternal knockout of Slc38a4/SNAT4 causes placental hypoplasia associated with intrauterine growth restriction in mice. Proc Natl Acad Sci U S A. 2019 Oct 15;116(42):21047-21053
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6403650
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved caspase-3 (Asp175) (5A1E) (#9664)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: The antibody used in this assay recognizes the cleaved form of the protein.
Results
Specimen S6C - WT ST: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: spongiotrophoblast Absent S6C upper WT Apoptotic cells are rarely observed.
Specimen S6C - MKO ST: embryonic day 13.5; Slc38a4em#Smtb/Slc38a4+ (more )
Note: maternal inheritance of knockout allele
Structure Level Pattern Image Note
TS21: spongiotrophoblast Absent S6C upper MKO Apoptotic cells are rarely observed.
Specimen S6C - PKO ST: embryonic day 13.5; Slc38a4em#Smtb/Slc38a4+ (more )
Note: paternal inheritance of knockout allele
Structure Level Pattern Image Note
TS21: spongiotrophoblast Absent S6C upper PKO Apoptotic cells are rarely observed.
Specimen S6C - Null ST: embryonic day 13.5; Slc38a4em#Smtb/Slc38a4em#Smtb (more )
Structure Level Pattern Image Note
TS21: spongiotrophoblast Absent S6C upper Null Apoptotic cells are rarely observed.
Specimen S6C - WT LB: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: labyrinthine zone Absent S6C lower WT Apoptotic cells are rarely observed.
Specimen S6C - MKO LB: embryonic day 13.5; Slc38a4em#Smtb/Slc38a4+ (more )
Note: maternal inheritance of knockout allele
Structure Level Pattern Image Note
TS21: labyrinthine zone Present Single cells S6C lower MKO Apoptotic cells are rarely observed.
Specimen S6C - PKO LB: embryonic day 13.5; Slc38a4em#Smtb/Slc38a4+ (more )
Note: paternal inheritance of knockout allele
Structure Level Pattern Image Note
TS21: labyrinthine zone Absent S6C lower PKO Apoptotic cells are rarely observed.
Specimen S6C - Null LB: embryonic day 13.5; Slc38a4em#Smtb/Slc38a4em#Smtb (more )
Structure Level Pattern Image Note
TS21: labyrinthine zone Absent S6C lower Null Apoptotic cells are rarely observed.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/24/2026
MGI 6.24 		The Jackson Laboratory